Current Organic Chemistry - Volume 21, Issue 23, 2017

Over the past decade, host-guest complexes have become increasingly targeted as new tools to bind organic molecules onto the surfaces of nanostructured materials. The chemical bond between organic molecules and nanostructures has evolved in recent years, from a covalent bond through simple anchor groups, to binding through highly tunable linker-anchor units, to binding through interfacial host-guest chemistry. Read More

Background: In this review, we summarized the relevance of anisotropic morphologies in the synthesis and applications of metal nanoparticles, including Janus nanoparticles. In recent years, the control over the shape of metal particles has successfully achieved. Non-spherical gold nanoparticles such as rods, wires, cubes, triangular prisms, decahedra, or octahedra exhibit unique properties that differ from those of s Read More

Background: Reaching the target cell has been the ultimate goal of nanoparticle-based drug delivery because many drugs do not have the adequate physicochemical properties to reach or be taken up by target cells. Therefore, site-specific drug delivery systems have been sought, aiming at overcoming many biological barriers, thus improving drug performance. Objective: Lipid nanoparticles emerged as a promisin Read More

Cancer is a disease in which cells show an atypical behavior and begin to divide abnormally without control. Furthermore, these cells can spread to other tissues and result in the development of new tumors. It is very difficult to find a treatment that discriminates between tumor cells and healthy cells because cancerous cells are from the person who has the disease and they are not an external and foreign pathogen easily recogn Read More

Background: Advances in the medicinal nanotechnology have given upward thrust to multifunctional efficient nanocarriers that can be engineered with tunable physico-chemical traits to deliver one or extra healing agent(s) appropriately and selectively to the most cancers cells, focusing on intracellular organellespecific drug delivery. Objective: Large pores of mesoporous silica nanoparticles allow the other particles to be fille Read More