Current Organic Chemistry - Volume 15, Issue 3, 2011

This review covers literature on organocatalyzed enantioselective α-heterofunctionalization of carbonyl compounds from 2006 to 2009. In this review, we will consider those reactions in which a new carbon-heteroatom bond is formed using a chiral organic molecule as catalyst, excluding those processes, which involve the modification on the hybridization of a previously functionalized carbonyl compound. Using this straigh Read More

Macrolides are produced by various Streptomyces strains and make up a large group of compounds among antibiotics used against various infectious diseases. There are many criteria of classification of compounds of this type but natural macrolides usually consist of 14- or 16- membered macrocyclic lactone rings and differ from each other by the type and number of sugar moieties attached as well as by their Read More

The publications appeared in the last eleven years on the topic of the preparation of organolithium reagents by nondeprotonating methodologies and starting from non-halogenated substrates have been covered in the present revision. In this part, the carbon-heteroatom bond cleavage under reductive conditions has been considered, carbon-oxygen and carbon-sulfur bond cleavages (both in acyclic or cyclic systems) being of Read More

Cyclic sulfites, sulfates and sulfamidates derived from saccharides have emerged as valuable and versatile synthons for the preparation of a wide variety of modified sugars and sugar related compounds owing to the combination of the easily and efficient formation of these chemical sulfur derivatives from diols and aminoalcohols with the high chemical stability and enhanced reactivity of those functions towards nucleophile Read More

A number of oxime reactivators have been synthesized and studied for the antidotal treatment of poisoning by toxic organophosphorus agents, and several oximes are currently available to reactivate the organophosphorus agents-induced acetylcholinesterase inhibition. However, there is no oxime with broad spectrum suitable for the antidotal treatment of poisoning with various organoposphorus warfare agents as well as ins Read More