Current Organic Chemistry - Volume 15, Issue 1, 2011

Supramolecular chemistry, coined as “beyond molecular” chemistry and based on the pioneering work of Donald J. Cram, Jean-Marie Lehn, and Charles J. Pedersen, aims to create novel structures and materials, fabricate nanomachines and small devices, mimic the functions of biomacromolecules and biosystems, and to illuminate the archebiont and make life ultimately. Generally, supramolecular chemistry incl Read More

Dendritic macromolecules are three-dimentional polymers with branch-on-branch topology of which dendrimers and hyperbranched polymers (HPs) are the two most researched subclasses. This paper reviews the recent progress of host-guest supramolecular chemistry in terms of various HPs and dendrimers. Because of the highly branched structure and the presence of internal space and binding sites, dendritic macromol Read More

This review summarizes recent work on the chemistry of inclusion complexes formed between redox active guests and cucurbit [n]uril hosts. The large majority of the surveyed research concerns the hosts cucurbit[7]uril (CB7) and cucurbit[8]uril (CB8), while the guests are 4,4'-bipyridinium (viologen) and ferrocene derivatives. The work includes dendronized guests, in which a guest residue is attached to a dendron in such a Read More

The use of calixarenes in asymmetric catalysis was described. The current progress of asymmetric catalysts based on calixarene scaffold for the enantioselective reactions including allylation, alkylation, addition of diethylzinc to benzaldehyde, Micheal-type addition, aldol reaction, hydrogenation, Friedal Crafts reaction, epoxidation, hydroformylation, and Biginelli reaction was illustrated. In these cases, calixarenes Read More

Regioisomers of calixarenes can be either produced in the reaction process with the same reactants or derived from the isomeric nucleophilic reagents. This article reviews the syntheses, different complexation abilities and self-assembly behaviors of the regioisomers in calixarenes.

Recently, separation science in the presence of cyclodextrins (CDs) has been paid more and more attention. Two important technologies based on CDs, molecularly imprinted polymers (MIPs) and ionic liquid (IL) cooperating approach, have been studied extensively and not been reviewed. MIPs are significant and important in separation processes. MIPs based on cyclodextrins (CD-MIPs) take advantage of unique properties of cyc Read More

The controllable functional encapsulation of cucurbit[n]urils (Q[n]s) to form supramolecular catalysts is reviewed. The relationship of the supramolecular catalytic activity with the structure of included guests and cucurbit[n]urils is documented and discussed. The controllable functional encapsulation is attributed to overall interactions of hydrophobic, ion-dipole and size effects of the cucurbit [n]urils. The accelerated and Read More

The aim of this article is to explore the molecular design, synthesis and construction of molecular shuttles based on conjugated organic molecules with photo-electronic activity by self-assembly techniques. The new functions of molecular shuttles, such as switching surface properties, protecting dyes and insulating molecular wires, controlling the energy transfer, controlling nanostructural morphologies, molecular transporting an Read More

Type 2 diabetes mellitus is a growing health problem across the world. Thiazolidinediones, a new class of oral antidiabetic agents, appear to be ideally suited for the treatment of this disease. The examination of the clinical efficacy of different thiazolidinediones has been extensive. This review summarizes the current state of the cut concerning the clinical use of different thiazolidinediones, starting from the first syntheti Read More

C-Glycosylphenols and -polyphenols occur widely in nature and present a variety of biological properties, namely antitumor, antibacterial and antidiabetic activities. Synthetic access to such structures relies mainly on efficient methodologies for phenols C-glycosylation. In the past few years major advances have been described addressing the use of Fries rearrangement to obtain a diversity of C-glycosyl compounds. Herein Read More