Current Organic Chemistry - Volume 10, Issue 2, 2006

Applications of organo-ruthenium derivatives in homogeneous catalysis have disclosed one of the cornerstones in the spectacular development of Organometallic Chemistry during the last decade. The special ability of ruthenium complexes to form a wide range of inorganic and organometallic complexes, featuring a wide scope of oxidation states, several coordination geometries and reactivity patterns, has triggered a growing Read More

Recent developments in the chemistry of η3-allylruthenium complexes (synthesis and reactivity) are described. Among different possible preparations, their straightforward formation via oxidative addition of allylic substrates occurs either at ruthenium(0) or ruthenium(II) centres. Subsequent reaction with an electrophile or a nucleophile is the basis of their ambiphilic involvement in catalysis. In this review, we focu Read More

Our recent studies on novel carbon-carbon bond forming reactions using propargylic alcohols catalyzed only by thiolate-bridged diruthenium complexes are reviewed from the viewpoint of organic synthesis. The reactions are substitutions of hydroxyl group of the alcohols with a variety of carbon-centered nucleophiles such as simple ketones, cyclic 1,3-dicarbonyl compounds, aromatic and heteroaromatic compounds, phen Read More

Recent progress in the Lewis acid catalysis of organic reactions by ruthenium complexes. The review focuses on reactions in which coordinatively unsaturated ruthenium species function as conventional Lewis acids, rather than those involving oxidation or reduction, such as in hydrogenations. Particular emphasis is placed on the development of asymmetric catalysts.

The present review reports on the chemistry of the bis(allyl)-ruthenium(IV) complexes [{Ru(η3:η3-C10H16)(μ- Cl)Cl}2] (C10H16 = 2,7-dimethylocta-2,6-diene-1,8-diyl) and [Ru(η:η2:η-C12H18)Cl2] (C12H18 = dodeca-2,6,10-triene- 1,12-diyl). Stoichiometric reactions allowing the preparation of a variety of organoruthenium(IV) and (II) derivatives, as well as the involvement of these species in a series of catalytic organic transform Read More

Recent advances in ruthenium-catalyzed ring closing metathesis are discussed, in context of both substrate and catalyst parameters. As well as thermodynamic (substrate) constraints on ring-closing, root causes and effects of non-ideal catalytic performance are examined. Key substrate parameters are outlined, with a particular focus on the balance between oligomerization and ring-closing in RCM macrocyclization reacti Read More

New imidazolium and imidazolinium salts were synthesized and their ability to act as stable N-heterocyclic carbene (NHC) ligand precursors was investigated in various ruthenium-catalyzed processes. Thus, 1,3- diarylimidazol(in)ium chlorides bearing the phenyl, 1-naphthyl, 4-biphenyl, 3,5-dimethylphenyl, 2-tolyl, 2,6- dimethylphenyl, 2,4,6-trimethylphenyl (mesityl), and 2,6-diisopropylphenyl substituents were prepared. They Read More

Recent advances in the development of ruthenium catalysts for the atom transfer radical addition of polyhalogenated compounds to olefins ('Kharasch reaction') are described. Three classes of homogeneous catalysts are discussed: halfsandwich complexes with η6-arene, η5-cyclopentadienyl or η5-carborane ligands, ruthenium complexes with alkylidene- or vinylidene ligands and polynuclear complexes. Furth Read More

This account describes the application of ruthenium complexes containing chiral tetradentate ligands PNNP, featuring a P 2N2 ligand set as catalysts for enantioselective reactions involving atom-transfer between the metal complex and a non-coordinated molecule. The five-coordinate 16-electron [RuCl(PNNP)]+ species and their octahedral analogues [RuCl(L)(PNNP)]+ have been used in the asymmetric epoxidation and Read More

This article reviews a novel approach to design heterogeneous Ru catalysts using hydroxyapatites and hydrotalcites, and their excellent catalytic performances for aerobic alcohol oxidations, carbon-carbon bond formations, and one-pot syntheses. The catalytic systems using the above heterogeneous Ru catalysts offer significant benefits in achieving simple and clean organic syntheses. Furthermore, the present prepara Read More