Synthesis of Chiral Heterocycles from Asymmetric Cascade Palladium Catalysis

This review updates the field of asymmetric cascade palladium catalysis applied to the synthesis of chiral heterocycles since 2019. It illustrates how much a diversity of chiral palladium catalysts promote unprecedented asymmetric domino reactions of many types, allowing direct access to a wide variety of complex and densely functionalized chiral heterocyclic molecules.