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2000
Volume 23, Issue 19
  • ISSN: 1385-2728
  • E-ISSN: 1875-5348

Abstract

This review summarizes the data published on the methods of preparation of β- keto amides as a versatile synthon for many heterocyclic rings and asymmetric urea derivatives. Based on the starting materials used for the synthesis of β-keto amides, eight methods were reported including β-keto acids and their derivatives, Meldrum’s acid and their derivatives, diketene, 2,6-dimethyl-1,3-dioxin-4-one derivatives (TMD), α-diazo ketones, enamines and enolates, acetamides and their derivatives and reduction of certain Passerini products.

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/content/journals/coc/10.2174/1385272823666191021120336
2019-08-01
2025-05-22
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