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- ISSN: 1385-2728
- E-ISSN: 1875-5348
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Organic Reactions under High Pressure: Efficient Multicomponent Synthesis of Novel Tricyclic Pyridazinonaphthyridine Derivatives under High Pressure
- Source: Current Organic Chemistry, Volume 22, Issue 3, Jan 2018, p. 268 - 275
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- 01 Jan 2018
Abstract
Background and Methodology: A series of pyridazino[5,4,3-de][1,6]naphthyridine derivatives of a new ring system (11a-k, 29a,b) were synthesized via novel multicomponent reaction under high pressure from 2-phenylhydrazono derivatives (1a-d), malononitrile and aromatic aldehydes (10a-h) or acetone (28). Conclusion: The structure of reaction products could be established by X-ray crystallography and a mechanism of reaction is proposed.
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