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- ISSN: 1385-2728
- E-ISSN: 1875-5348
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Applications of Mannich Reaction in Total Syntheses of Natural Products
- Source: Current Organic Chemistry, Volume 18, Issue 22, Nov 2014, p. 2857 - 2891
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- 01 Nov 2014
Abstract
Mannich reaction has captured great attention and found usefulness as one of the most powerful synthetic methodologies for the carbon-carbon bond formation. Mannich reaction is also found to have a variety of applications in the total syntheses of natural and biologically active compounds in their crucial C-C bond forming steps. The present review is focused on the applications of Mannich reaction in total syntheses of natural products and some other complex targets.
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