Strategies for Functionalized Benzocycloheptene Amines Synthesis

Functionalized benzocycloheptenes are one of the most important classes of bicyclic framework that have been critically investigated in different areas of biological activities. Due to interesting skeleton and activities, synthetic chemists were inspired to synthesize them for better understanding of the basic knowledge associated with these compounds. Thus, this review aims to provide insight approaches for construction and functionalization of benzocycloheptene amines and renders useful details for further progress in the area of synthetic methodology. We believe that functionalized benzocycloheptene amine compounds and their various co-components, highlight the existence of numerous potential leads for the development of novel bioactive agents.