Polymeric Supramolecular Materials and Their Biomedical Applications

The supramolecular self-assembly of polymer chains by specific, directional, and dynamic non-covalent interactions, including hydrogen bonds, host-guest interactions, and amphiphilic associations, has led to the development of novel polymeric supramolecular materials (PSMs). PSMs in the form of micelles, fibers, and hydrogels, which exhibit unique chemical, physical, and biological properties, have been fabricated and shown to have great potential in biomedical applications. This review focuses on recent advances in the construction, as well as biomedical applications, of PSMs, such as in drug delivery matrices, tissue engineering scaffolds, and biosensors.