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Volume 15, Issue 16
  • ISSN: 1385-2728
  • E-ISSN: 1875-5348

Abstract

Organosillicon reagents have been found as versatile catalysts or promoters for a broad range of organic reactions due to their special properties of multifunction. An important application of organosilicon reagents is in the research field of multicomponent reactions (MCRs), which provides a vast number of practical synthesis for different molecular libraries. We present in this review the recent research progress of MCRs employing organosillicon reagents as catalysts or promoters for the first time.

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/content/journals/coc/10.2174/138527211796378479
2011-08-01
2025-05-20

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  • Article Type:     Research Article
Keyword(s): Carbon Nucleophiles; catalysis; chemo-selective; cyclic ketones; diastereoseletivity; dimethyl acetylene dicarboxylate (DMAD); hexamethyl disiloxane (HMDS); multicomponent reactions; multicomponent reactions (MCRs); Organosilicon; promotion; tetrahydro pyrimidinones (THPMs); TMSOTf; trimethylsilyl chloride (TMSCl); trimethylsilyl iodide (TMSI)

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