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Volume 13, Issue 10
  • ISSN: 1385-2728
  • E-ISSN: 1875-5348

Abstract

2-Isothiocyanatobenzonitrile (ITCB) and isocyanatobenzonitrile (ICB) represent versatile difunctional building blocks containing a nitrile and an isothiocyanate or an isocyanate function, respectively. The present review provides an account of the chemistry of ITCB and ICB. This includes a number of one-pot cyclizations which provide a convenient access to a variety of pharmacologically important heterocycles.

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/content/journals/coc/10.2174/138527209788680763
2009-07-01
2025-05-03

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  • Article Type:     Research Article
Keyword(s): 2-Isothiocyanatobenzonitrile (ITCB); Building Blocks; heterocycles; isocyanate function; isocyanatobenzonitrile (ICB); one-pot cyclizations; Organic Synthesis

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