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1,4-Dihydropyridines are of great chemical and pharmacological significance as evidenced from a chapter written by Drs Reddy and Chakravarty form Dr Reddy's Laboratories Ltd, Hyderabad, India. It is well-known that carbon nucleophiles are useful in organic synthesis in general and in heterocyclic synthesis in particular. In the final comprehensive chapter Professors Madkour and Elgazwy from Ain Shams University, Cairo, Egypt discusses new developments in this field.