Vitamin D Focused Approach to Nutritional Therapy for the Management of SARS-CoV-2 Pandemic: A Review

Background: In several studies, Vitamin D supplementation was found useful against the highly infectious SARS-CoV-2 to reduce the mortality rate and severity of its infection. Viral replication was also found to be affected negatively by vitamin D administration. Objective: The literature was reviewed with an aim to evaluate the efficacy of the therapeutic approach of nutrition involving intervention of Vitamin D towards decreasing the severity of prevailing pandemic of SARS-CoV-2. Methods: A background research of literature was performed using the keywords “SARS-CoV- 2”, “COVID-19”, “nutritional therapy”, “Vitamin D”, “immunity”, “AEC2 receptors” and “RAS” in the Pubmed and Google Scholar. Results: This literature was review suggested that if combined with medical sciences, this nutritional therapy approach can end up as an influential solution to reduce the severity of SARSCoV- 2 infection, which is a prevailing pandemic. A combination of assessment, supplementation of this required micro-nutrient (Vitamin D), and monitoring can be used to aid the immune system of COVID-19 patients. Conclusion: Nutritional therapy with Vitamin D as a major factor can be used to increase the immunity of an individual to fight against the highly infectious SARS-CoV-2. However, the actual mechanism of how Vitamin D supplementation functions to improve the health of an individual is yet unclear.