A Review on Experimental Models for Screening Plant Food and Human Nutrition

Background: Malnutrition is a common universal health problem, but it is more chronic for developing countries. Due to increasing nursing home recognition, it has become a major research priority internationally. Lower immunity due to malnutrition has a high prevalence and other clinical consequences. Disease-related malnutrition is potentially severe for patients and has a high economic impact on the healthcare system. Objectives: The aim of this review is to describe various experimental models employed for the evaluation of malnutrition and immunomodulatory activities. Methods: This review is intended for both clinicians and researchers to describe several screening methods that better suit the type of lead compounds and are suitable for screening molecules for better treatment outcomes. Results: This review focuses on the various screening methods for the evaluation of malnutrition and suggests their implications in the research and practice. Conclusion: The malnutrition-induced diseases cause a rise in health care costs that can be minimized with an introduction of drugs and nutritional supplements by selecting proper screening models and performing exhaustive research.