Current Nanoscience - Volume 8, Issue 2, 2012

Aiming at the development of a stable drug carrier for bicalutamide (BT), we prepared various lipid nano-emulsions (LNEs) from a lipid mixture of soybean oil, phosphatidylcholine, sodium palmitate and sucrose palmitate (SP). These LNEs had mean particle size of approximately 50 nm and zeta potential (ζ) of -40 to -30 mV and were investigated their stability in saline solution and in bovine serum by using the dynamic light s Read More

The gastrin-releasing peptide receptor (GRP-r) is overexpressed in breast and prostate cancer, and Lys3-bombesin is a peptide that binds with high affinity to the GRP-r. HIV Tat(49-57) is a cell-penetrating peptide that reaches the DNA. In cancer cells,177Lu shows efficient cross-fire effect, while 99mTc that is internalised to cancer cell nuclei acts as an effective system of targeted radiotherapy because of the Auger and IC electro Read More

Quantum Dots (QDs) for bio-imaging applications need to be water-stable, exhibit high brightness and physico-chemical stability in order to prevent the leakage of toxic ions. In the present work, the direct synthesis of water-soluble CdSe quantum dots and their surface functionalization were achieved through a micro-wave assisted approach in aqueous phase. Glutathione, an essential tri-peptide, was used to functionalize the Read More

Microspherical and uniform LiFePO4/C was successfully prepared by a spray drying method assisted with template. The materials were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The as-synthesized LiFePO4/C was used as cathode materials for battery evaluation. The material prepared with PVA as template possess perfect olivine structure of lithium ion battery with uniform size Read More

In this work, Polyaniline (PANI) microtubes and magnetite (Fe3O4) nanoparticles have been synthesized by using ammonium persulphate as oxidant via in-situ chemical oxidative polymerization in the presence of organic sulfonic acid. The resulting PANI / Fe3O4 nanocomposite materials have been characterized by X-ray diffraction, UV-visible spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy Read More

The direct mix of aqueous FeCl3 and o-phenylenediamine (OPD) solutions at room temperature leads to supramolecular microfibrils of OPD dimers generated by the oxidation of OPD monomers by FeCl3. In this paper, we demonstrate that the subsequent treatment of such microfibrils with a HAuCl4 aqueous solution leads to Au nanoparticle (AuNP)-decorated nanoplates. The possible formation mechanism involved is also disc Read More

Hierarchical single-crystalline β-SiC nanowires were synthesized by simply heating carbonaceous silica xerogel. A fairly high density of stacking faults was observed perpendicular to [111] growth direction of the hierarchical nanowires. A possible vapor-solid growth mechanism for the hierarchical nanowires was discussed. The photoluminescence spectrum of hierarchical SiC nanowires at room temperature shows two Read More

This paper describes a nano-heat transfer fluid (NHTF) consisting of a novel mixture of alkali metal nitrate salt eutectic doped with silica nanoparticles at 0.5% mass concentration with a low melting point, high thermal stability and high specific heat capacity. These properties produce a wide operating range Heat Transfer Fluid and enable effective thermal storage for parabolic trough concentrating solar power plants a Read More

Substituted strontium ferrites SrFe12-xCrx/2Alx/2O19 (x=0–2.5) / multi-walled carbon nanotubes (MWCNTs) nanocomposites were prepared by a sol- gel method. The XRD patterns show a relatively weak peak at around 26º, corresponding to the graphite (002) lattice plane of the MWCNTs. The peak of Fourier transform infrared spectroscopy (FTIR) at about 1730 cm-1 could be assigned to the stretching mode of carbonyl gr Read More

We illustrate that the redistribution of a compatible homopolymer blended in a certain block copolymer results in a shift of phase boundaries and in the stabilization of well-ordered structures by using polystyrene (PS) homopolymer blended in polystyrenepolybutadiene- polystyrene triblock copolymer (SBS1102) as a model system. The addition of the homopolymer into the asymmetric triblock copolymer increases the perio Read More

Statins can inhibit growth of malignant cells. Aims: The aim of the present work was to increase efficacy of simvastatin on chronic meyloid leukemia K562 cells by folate targeted solid lipid nanoparticles (SLN). Methodology: Folate targeting agent was prepared by chemical reaction between folic acid and dodecylamine. Folate targeted SLNs of simvastatin were prepared by an emulsification- solvent evaporation method. Then cyto Read More

An aqueous suspension containing magnetic nanoparticles is not stable because the nanoparticles aggregate. As the aggregates size increases and the number of particles in suspension decreases, the rheological properties of the nanofluid, which are important for biomedical applications, change tremendously. Modified versions of the SLS and DLS experiments were used to monitor the nanoparticle aggregation and the re Read More

(3-Chloro-7-methoxyfuro[2,3-b]-quinolin-4-yl)-(4-methoxyphenyl)amine (CYL), a chemotherapeutic agent, is an analogue of amsacrine. The water insolubility of CYL limits its delivery and thus its application. The aim of the study was to utilize solid lipid nanoparticles (SLNs) to improve the delivery of CYL, and investigate its biodistribution behavior in an animal model. Characterizations of SLNs were evaluated including the p Read More

This paper reports the fabrication of a carbon nanotubes based carbon mono-oxide gas sensor. Initially, iron catalyzed carbon nanotubes were grown on silicon oxide grown silicon substrate using low pressure chemical vapor deposition. Morphology and microstructure of these CNTs were studied by field emission scanning electron microscopy (FESEM) and high resolution transmission electron microscopy (HRTEM). Morphol Read More

Green synthesis of metal nano particles is an emerging branch of nanotechnology, very cost effective, eco-friendly, thus, can be an economic and efficient alternative for the large-scale synthesis of nano particles. This study focuses on the bio synthesis property of Peanut (Arachis hypogaea L.) leaf extract in the synthesis of silver nano particles at room temperature without using any harmful reducing agents and its antibacterial Read More

Magnetic iron oxide nanoparticles (MION) with unique surface properties have been widely used in various fields of sciences such as biomedicine. In addition to complicated chemical methods of iron oxide nanoparticles synthesis, there are great concerns regarding their application in vivo. The aims of this study were to investigate both the biologic synthesis of iron nanoparticles and toxic effects of MIONs on red blood cells from Read More

In this communication, we report a new method for effective immobilization of Ag nanoparticles (AgNPs) on thiolated singlestranded DNA (thiol-ssDNA) modified Au electrode (AuE) surface via coordination interactions between the nitrogen atoms of DNA bases and AgNPs. It suggests that the AgNP-immobilized AuE exhibits notable catalytic performance for H2O2 reduction and the loading of AgNPs on the AuE surface and ther Read More

We, report for the first time, the synthesis and kinetics of Ni and Fe3O4 nanobioconjugates obtained by covalent conjugation of nanoparticles to lactate dehydrogenase (LDH). The conjugation reaction was performed using bis(sulfosuccinimidyl) suberate (BS3) as a cross-linking agent. The kinetics of discrete conjugates was studied through conversion of lactate and pyruvate and subsequent reduction of NAD+ to NADH at 3 Read More

A careful comparison of the experimental results reported in the literature reveals different variations of the melting temperature even for the same materials. Though there are different theoretical models, thermodynamic model has been extensively used to understand different variations of size-dependent melting of nanoparticles. There are different hypotheses such as homogeneous melting (HMH), liquid nucleation and Read More

Dye-sensitized solar cells are electrochemical devices with very interesting properties that provide an alternative to the conventional semiconductor solar cell technology. However, the details of the charge transport mechanisms, which include both electronic and ionic transport, are not yet fully understood. In this paper, we present a novel approach to dye-sensitized solar cell modeling and simulation which is bas Read More