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Contribution of the Activated mTOR-STAT3 Pathway to the Pathogenesis of Focal Cortical Dysplasia Type IIIa in Pediatric Patients through Astrocyte Proliferation Mediation
Authors: Jiangya Wang, Jiang Wu, Yang Li, Yuanyuan Lv, Xinying Zhang and Lin KangAvailable online: 04 October 2024More LessObjective The aim of this study was to detect the association between the mTOR-STAT3 pathway and focal cortical dysplasia type IIIa (FCD IIIa) in children. Methods A retrospective review was conducted based on 26 pediatric patients diagnosed with FCD IIIa who underwent surgical intervention. These patients were selected from a cohort of 157 individuals presenting with temporal lobe epilepsy. For comparative anal Read More
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The AMPK/cAMP Metabolic Signaling Axis as a Possible Therapeutic Target for Diabetes
Available online: 09 September 2024More LessDiabetes is a complex disease, despite the availability of numerous treatments, its progression and complications can only be mitigated and managed to a certain extent. After the onset, diabetes cannot be reversed. Its global expansion makes it challenging for governments to control the considerable costs of treating people with diabetes. Many studies have been carried out by widely recognized pharmaceutical comp Read More
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