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Microwave-assisted Organo-catalyzed C-C and C-X (Heteroatom) Bondforming Reactions: An Overview
- Source: Current Microwave Chemistry, Volume 8, Issue 3, Dec 2021, p. 173 - 203
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- 01 Dec 2021
Abstract
Organocatalysis is a term used to describe small organic molecules that exclusively include carbon, hydrogen, oxygen, nitrogen, sulphur, and phosphorus atoms that are used to speed up chemical reactions. The researchers demonstrated a large area of applications in various organic transformations catalysed by the organocatalysts due to their lower moisture sensitivity in air, easy abundance, less polluting nature, noninterference with the final product, and costeffectiveness. This highlights high demand and direct benefits in pharmaceutical intermediate and fine chemical manufacturing compared to other conventional transition metal and enzyme catalysts. This review article intends to compile literature-reported applications of the microwave accelerated organocatalyzed carbon-carbon and carbon-heteroatom bond formation reactions.