Skip to content
2000
Volume 29, Issue 35
  • ISSN: 0929-8673
  • E-ISSN: 1875-533X

Abstract

Background: Obsessive-compulsive disorder is a highly debilitating psychiatric disorder with a high rate of treatment resistance. Biomarkers for obsessive-compulsive disorder may assist clinicians by predicting response to treatments and prognosis. Objective: The aim of the study was to review the literature with regards to two of the more easily ascertainable and relatively inexpensive physiological biomarkers, i.e., heart rate variability and electroencephalography. Methods: A narrative review of the literature was conducted. Results: Decreased heart rate variability has been associated with increased symptom severity of obsessive-compulsive disorder. Findings from electroencephalography have also predicted response to pharmacotherapy and it is likely that biomarkers for OCD will have their greatest utility in predicting response to different pharmacological agents. However, the number of studies is small and results are inconsistent. Conclusion: More research is required to determine whether heart rate variability and electrophysiological studies play a clinical role as biomarkers for obsessive-compulsive disorder.

Loading

Article metrics loading...

/content/journals/cmc/10.2174/0929867329666211217094941
2022-10-01
2025-06-15
Loading full text...

Full text loading...

/content/journals/cmc/10.2174/0929867329666211217094941
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test