Skip to content
2000
Volume 30, Issue 5
  • ISSN: 0929-8673
  • E-ISSN: 1875-533X

Abstract

Copper is an essential element for most aerobic organisms, with an important function as a structural and catalytic cofactor, and in consequence, it is implicated in several biological actions. The relevant aspects of chemistry and biochemistry and the importance of copper compounds in medicine give us a comprehensive knowledge of the multifaceted applications of copper in physiology and physiopathology. In this review, we present an outline of the chemistry, and the antitumor properties of copper complexes on breast, colon, and lung cancer cells focus on the role of copper in cancer, the relationship between structure-activity, molecular targets, and the study of the mechanism of action involved in its anticancer activity. This overview is expected to contribute to understanding the design, synthesis, and uses of copper complexes as antitumor agents in the most common cancers.

Loading

Article metrics loading...

/content/journals/cmc/10.2174/0929867328666211117094550
2023-02-01
2025-06-15
Loading full text...

Full text loading...

/content/journals/cmc/10.2174/0929867328666211117094550
Loading

  • Article Type:
    Review Article
Keyword(s): cancer; cisplatin; Copper; mechanism of action; SAR; tumors
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test