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Analysis of Molecular Targets of Mycobacterium tuberculosis by Analytical Ultracentrifugation
- Source: Current Medicinal Chemistry, Volume 18, Issue 9, Mar 2011, p. 1276 - 1285
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- 01 Mar 2011
Abstract
The interest in analytical ultracentrifugation (AUC) to analyze protein structural parameters and interactions has increased in the past decades as a result of several developments on new generation instrumentation and data analysis tools. In this article, we review AUC principles and applications to study proteins, emphasizing molecular targets of Mycobacterium tuberculosis.
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