Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives

F. Fulop; I. Szatmari; E. Vamos; D. Zadori; J. Toldi; L. Vecsei

doi:10.2174/092986709789909602

ISSN: 0929-8673
E-ISSN: 1875-533X

Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives
Authors: F. Fulop¹, I. Szatmari², E. Vamos³, D. Zadori⁴, J. Toldi⁵ and L. Vecsei⁶
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¹ Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary. ² Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary. ³ Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary. ⁴ Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary. ⁵ Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary. ⁶ Institute of Pharmaceutical Chemistry and Research Group for Stereochemistry, Hungarian Academy of Sciences, University of Szeged, H-6720 Szeged, Eotvos u. 6, Hungary.
Source: Current Medicinal Chemistry, Volume 16, Issue 36, Dec 2009, p. 4828 - 4842
DOI: https://doi.org/10.2174/092986709789909602
- Available online: 01 Dec 2009

Abstract

The syntheses and transformations of 4-hydroxyquinoline-2-carboxylic acid, kynurenic acid, are reviewed, and special attention is paid to the pharmacological activities and pharmaceutical applications of its derivatives.

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2009-12-01

2025-05-06

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Article Type: Research Article

Keyword(s): diabetes mellitus; hypertension; Kynurenic acid; kynurenic acid derivatives; neurological disorders; retinal damage; schizophrenia

Syntheses, Transformations and Pharmaceutical Applications of Kynurenic Acid Derivatives

Abstract

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