Skip to content
2000
image of Bibliometric Analysis of Research on Traditional Chinese Medicine Treatment of Myocardial Infarction from 2007 to 2024 Based on the Web of Science Database

Abstract

Background

Myocardial infarction (MI) is a common critical syndrome in the late development of cardiovascular diseases (CVDs), and traditional Chinese Medicine (TCM) treatment has become an essential branch in this field.

Objective

This study aimed to use bibliometric methods to examine the research trajectory of TCM treatment of MI from 2007 to 2024 from a multidimensional perspective and analyse its characteristics, hotspots, and frontiers.

Methods

This study used the search formula TS OR TI OR AB OR A (“traditional Chinese medicine” or “Chinese medicine” or “TCM” or “traditional medicine, Chinese” or ” Chinese traditional medicine” or “Chinese medicine, traditional”) AND TS OR TI OR AB OR AK (“myocardial infarction” or “myocardial infarctions” or ” infarction, myocardial” or “infarctions, myocardial” or “myocardial infarct” or “MI”) to find the Web of Science Core Collection (WOSCC) of relevant studies from 01/01/2007 to 04/29/2024. Target literature records were analysed and graphed using CiteSpace, VOSviewer, and Scimago Graphica.

Results

A total of 754 records were obtained and 399 records were finally retained after screening. Countries, institutions, authors, and journals were visually analyzed. The current research hotspots and frontiers included , ischemia-reperfusion injury, pathway, molecular docking, and network pharmacology.

Conclusion

This research study would enrich the researchers' understanding of the existing research methodology and future development trends and provide a more efficient research methodology for the research on the mechanism of action of TCM for the treatment of MI and its clinical trials.

Loading

Article metrics loading...

/content/journals/cmc/10.2174/0109298673362741250128065027
2025-02-18
2025-03-31
Loading full text...

Full text loading...

References

  1. Varghese T.P. Genetic biomarkers of cardiovascular disease. Curr. Probl. Cardiol. 2024 49 7 102588 10.1016/j.cpcardiol.2024.102588
    [Google Scholar]
  2. Sagris M. Antonopoulos A.S. Theofilis P. Oikonomou E. Siasos G. Tsalamandris S. Antoniades C. Brilakis E.S. Kaski J.C. Tousoulis D. Risk factors profile of young and older patients with myocardial infarction. Cardiovasc. Res. 2022 118 10 2281 2292 10.1093/cvr/cvab264 34358302
    [Google Scholar]
  3. Luo C. Ruan Y. Sun P. Wang H. Yang W. Gong Y. Wang D. The role of transcription factors in coronary artery disease and myocardial infarction. Front. Biosci. Landmark 2022 27 12 329 10.31083/j.fbl2712329 36624938
    [Google Scholar]
  4. Zhao X. Yang F. Wu H. Fan Z. Wei G. Zou Y. Xue J. Liu M. Chen G. Zhilong Huoxue Tongyu capsule improves myocardial ischemia/reperfusion injury via the PI3K/AKT/Nrf2 axis. PLoS One 2024 19 4 e0302650 10.1371/journal.pone.0302650 38687744
    [Google Scholar]
  5. Liu Y. Li L. Wang Z. Zhang J. Zhou Z. Myocardial ischemia-reperfusion injury; Molecular mechanisms and prevention. Microvasc. Res. 2023 149 104565 10.1016/j.mvr.2023.104565 37307911
    [Google Scholar]
  6. Yang Y. Wu A. Deng A.N. Liu H. Lan Q. Mazhar M. Xue J.Y. Chen M.T. Luo G. Liu M.N. Macrophages after myocardial infarction: Mechanisms for repairing and potential as therapeutic approaches. Int. Immunopharmacol. 2024 143 Pt 3 113562 10.1016/j.intimp.2024.113562 39536484
    [Google Scholar]
  7. Chan M.Y. Efthymios M. Tan S.H. Pickering J.W. Troughton R. Pemberton C. Ho H.H. Prabath J.F. Drum C.L. Ling L.H. Soo W.M. Chai S.C. Fong A. Oon Y.Y. Loh J.P. Lee C.H. Foo R.S.Y. Johnson A.M.A. Pilbrow A. Richards A.M. Prioritizing candidates of post–myocardial infarction heart failure using plasma proteomics and single-cell transcriptomics. Circulation 2020 142 15 1408 1421 10.1161/CIRCULATIONAHA.119.045158 32885678
    [Google Scholar]
  8. Bai G. Yang J. Liao W. Zhou X. He Y. Li N. Zhang L. Wang Y. Dong X. Zhang H. Pan J. Lai L. Yuan X. Wang X. MiR-106a targets ATG7 to inhibit autophagy and angiogenesis after myocardial infarction. Animal Model. Exp. Med. 2024 7 4 408 418 10.1002/ame2.12418 38807299
    [Google Scholar]
  9. Titova O.E. Yuan S. Byberg L. Baron J.A. Lind L. Michaëlsson K. Larsson S.C. Plasma proteome and incident myocardial infarction: Sex-specific differences. Eur. Heart J. 2024 45 43 4647 4657 10.1093/eurheartj/ehae658 39397782
    [Google Scholar]
  10. Wang J. Zou J. Shi Y. Zeng N. Guo D. Wang H. Zhao C. Luan F. Zhang X. Sun J. Traditional chinese medicine and mitophagy: A novel approach for cardiovascular disease management. Phytomedicine 2024 128 155472 10.1016/j.phymed.2024.155472 38461630
    [Google Scholar]
  11. Curfman G. Traditional chinese medicine for ST-segment elevation myocardial infarction. JAMA 2023 330 16 1546 10.1001/jama.2023.19712 37874581
    [Google Scholar]
  12. Yang Y. Li X. Chen G. Xian Y. Zhang H. Wu Y. Yang Y. Wu J. Wang C. He S. Wang Z. Wang Y. Wang Z. Liu H. Wang X. Zhang M. Zhang J. Li J. An T. Guan H. Li L. Shang M. Yao C. Han Y. Zhang B. Gao R. Peterson E.D. Yang Y. Wu J. Wang C. He S. Wang Z. Wang Y. Jing Y. Liu L. Zhang X. Pei H. Xue Y. Zheng G. Wang C. Zhao Z. Zheng Y. Duan B. Zhang G. Liu H. Wang Z. Fan Z. Cao W. Zhang H. Qi X. Wang X. Wu G. Gao F. Bie Z. Yue L. Hong H. Qian J. Dai B. Dou W. Yue L. Zhan Z. Liu M. Gao X. Lian Y. Zheng Y. Zhang J. Man R. Dong P. Wu L. Deng J. Guo Y. Zhang M. Li J. Wang Z. Dai P. Siri G. Xu Q. Li X. Li K. Han S. Wang H. Li X. Yang P. Zhang H. Liu Y. Xin B. Zhang M. Cao Z. Zhang M. Ma G. Wang L. Song J. Li W. Li H. Shang Z. Feng O. Zhang H. Gao H. Bao R. Wang F. Shang L. Qin L. Wang J. Ma G. Cui J. Wang S. Cheng F. Zhang S. Liu X. Cha C. Sun M. Han W. Lu H. Wang H. Zhu H. Wang W. Wang Z. Guo Y. Zhang H. Shao Z. Cui X. Lu C. Lv Z. Zhang J. Cui G. Zhang H. Han Y. Liu W. Zhou B. Ge H. Zhang L. Chen T. Niu B. Mu B. Zhang J. Guan H. Chun Y. Zhang H. Li F. Yin S. Wang X. Zou X. Song J. Hong L. Zheng M. Jiang B. Liu S. Zhu R. Liu W. Zhang J. Wu B. Wu Z. Fang Q. Yuan Z. Gao C. Jiang H. Li X. Bu P. Gao W. Liu H. Xian Y. Gao R. Zhang B. Han Y. Ge J. Peterson E. Chen S. Pu J. Zheng Q. Huang C. Shen W. Wu Y. Yao C. Yan X. Shang M. Fan X. Cheng H. Chang W. Wang H. Li Z. Zhai W. Zhu Z. Li H. Wang J. Tao J. Xu B. Sun M. Wu F. Zou T. Chang Y. Yin P. Shen J. Zhang Y. Huang Y. Chen G. Li X. Xu Y. Yang J. Zhang H. Jin C. Wang M. Traditional chinese medicine compound (Tongxinluo) and clinical outcomes of patients with acute myocardial infarction. JAMA 2023 330 16 1534 1545 10.1001/jama.2023.19524 37874574
    [Google Scholar]
  13. mei D.X. hua J.Z. yuan L.K. jun M.Z. cai H.S. Traditional Chinese medicine for myocardial infarction: An overview. Int. J. Clin. Pract. 2013 67 12 1254 1260 10.1111/ijcp.12172 24246206
    [Google Scholar]
  14. Wang Y. Xue Y. Guo H. Intervention effects of traditional Chinese medicine on stem cell therapy of myocardial infarction. Front. Pharmacol. 2022 13 1013740 10.3389/fphar.2022.1013740 36330092
    [Google Scholar]
  15. Hao P. Jiang F. Cheng J. Ma L. Zhang Y. Zhao Y. Traditional chinese medicine for cardiovascular disease: Evidence and potential mechanisms. J. American College Cardiol. 2017 69 24 2952 2966 10.1016/j.jacc.2017.04.041
    [Google Scholar]
  16. Lv J. Li Y. Shi S. Liu S. xu X. Wu H. Zhang B. Song Q. Frontier and hotspot evolution in cardiorenal syndrome: A bibliometric analysis from 2003 to 2022. Curr. Probl. Cardiol. 2023 48 8 101238 10.1016/j.cpcardiol.2022.101238 35500729
    [Google Scholar]
  17. Kokol P. Meta approaches in knowledge synthesis in nursing: A bibliometric analysis. Nurs. Outlook 2021 69 5 815 825 10.1016/j.outlook.2021.02.006 33814160
    [Google Scholar]
  18. Ge Y. Chao T. Sun J. Liu W. Chen Y. Wang C. Frontiers and hotspots evolution in psycho-cardiology: A bibliometric analysis from 2004 to 2022. Curr. Probl. Cardiol. 2022 47 12 101361 10.1016/j.cpcardiol.2022.101361 35995242
    [Google Scholar]
  19. Dwyer T. Network visualization as a higher-order visual analysis tool. IEEE Comput. Graph. Appl. 2016 36 6 78 85 10.1109/MCG.2016.117 27893370
    [Google Scholar]
  20. Eck V.N.J. Waltman L. Software survey: VOSviewer, a computer program for bibliometric mapping. Scientometrics 2010 84 2 523 538 10.1007/s11192‑009‑0146‑3 20585380
    [Google Scholar]
  21. Luo H. Cai Z. Huang Y. Song J. Ma Q. Yang X. Song Y. Study on pain catastrophizing from 2010 to 2020: A bibliometric analysis via citespace. Front. Psychol. 2021 12 759347 10.3389/fpsyg.2021.759347 34975649
    [Google Scholar]
  22. Chen Y.H. Yin M.Q. Fan L.H. Jiang X.C. Xu H.F. Zhang T. Zhu X.Y. Bibliometric analysis of traditional Chinese medicine research on heart failure in the 21st century based on the WOS database. Heliyon 2023 9 1 e12770 10.1016/j.heliyon.2022.e12770 36691539
    [Google Scholar]
  23. Li H. Sureda A. Devkota H.P. Pittalà V. Barreca D. Silva A.S. Tewari D. Xu S. Nabavi S.M. Curcumin, the golden spice in treating cardiovascular diseases. Biotechnol. Adv. 2020 38 107343 10.1016/j.biotechadv.2019.01.010 30716389
    [Google Scholar]
  24. Benameur T. Gaban F.S.V. Giacomucci G. Filannino F.M. Trotta T. Polito R. Messina G. Porro C. Panaro M.A. The effects of curcumin on inflammasome: Latest update. Molecules 2023 28 2 742 10.3390/molecules28020742 36677800
    [Google Scholar]
  25. Li S. Guo L.Z. Kim M.H. Han J.Y. Serebruany V. Platelet microRNA for predicting acute myocardial infarction. J. Thromb. Thrombolysis 2017 44 4 556 564 10.1007/s11239‑017‑1537‑6 29030746
    [Google Scholar]
  26. Ge C. Meng D. Peng Y. Huang P. Wang N. Zhou X. Chang D. The activation of the HIF-1α-VEGFA-Notch1 signaling pathway by Hydroxysafflor yellow A promotes angiogenesis and reduces myocardial ischemia–reperfusion injury. Int. Immunopharmacol. 2024 142 Pt A 113097 10.1016/j.intimp.2024.113097 39260311
    [Google Scholar]
  27. Fu Y.P. Zou Y.F. Lei F.Y. Wangensteen H. Inngjerdingen K.T. Aconitum carmichaelii Debeaux: A systematic review on traditional use, and the chemical structures and pharmacological properties of polysaccharides and phenolic compounds in the roots. J. Ethnopharmacol. 2022 291 115148 10.1016/j.jep.2022.115148 35240238
    [Google Scholar]
  28. Wang Y. Wang X. Wang J. Li C. Zhao G. Zheng C. Shi X. Wang X. Wang K. Wu W. Zhang Z. Liu H. Zhou H. Lin F. Ruan X. Zhao J. Wang S. Li X. Nie S. Li X. Huang J. Sun H. Pian L. Xing W. Li B. Yu R. Xing Z. Song Y. Luo Y. Wang D. Xie Y. Zhang J. Zhu M. A multicenter, randomized, double-blind, placebo-controlled trial to evaluate the effect of Tongmai Yangxin pill on ventricular remodeling in acute anterior STEMI patients after primary PCI. Phytomedicine 2024 135 156133 10.1016/j.phymed.2024.156133 39489990
    [Google Scholar]
  29. Ge S. Wu S. Yin Q. Tan M. Wang S. Yang Y. Chen Z. Xu L. Zhang H. Meng C. Xia Y. Asakawa N. Wei W. Gong K. Pan X. Ecliptasaponin A protects heart against acute ischemia-induced myocardial injury by inhibition of the HMGB1/TLR4/NF-κB pathway. J. Ethnopharmacol. 2024 335 118612 10.1016/j.jep.2024.118612 39047883
    [Google Scholar]
  30. Fu J. Chang L. Harms A.C. Jia Z. Wang H. Wei C. Qiao L. Tian S. Hankemeier T. Wu Y. Wang M. A metabolomics study of Qiliqiangxin in a rat model of heart failure: A reverse pharmacology approach. Sci. Rep. 2018 8 1 3688 10.1038/s41598‑018‑22074‑6 29487344
    [Google Scholar]
  31. Lai E.J. Grubisic M. Palepu A. Quan H. King K.M. Khan N.A. Cardiac medication prescribing and adherence after acute myocardial infarction in Chinese and South Asian Canadian patients. BMC Cardiovasc. Disord. 2011 11 1 56 10.1186/1471‑2261‑11‑56 21923931
    [Google Scholar]
  32. Zhang J. Li W. Xue S. Gao P. Wang H. Chen H. Hong Y. Sun Q. Lu L. Wang Y. Wang Q. Qishen granule attenuates doxorubicin-induced cardiotoxicity by protecting mitochondrial function and reducing oxidative stress through regulation of Sirtuin3. J. Ethnopharmacol. 2024 319 Pt 1 117134 10.1016/j.jep.2023.117134 37714227
    [Google Scholar]
  33. An N. Zhang G. Li Y. Yuan C. Yang F. Zhang L. Gao Y. Xing Y. Promising antioxidative effect of berberine in cardiovascular diseases. Front. Pharmacol. 2022 13 865353 10.3389/fphar.2022.865353 35321323
    [Google Scholar]
  34. Guo H. Li P. Zhao J. Xin Q. Miao Y. Li L. Li X. Wang S. Mo H. Zeng L. Ju Z. Liu Z. Shen X. Cong W. Sheng Mai Yin shows anti-fatigue, anti-hypoxia and cardioprotective potential in an experimental joint model of fatigue and acute myocardial infarction. J. Ethnopharmacol. 2024 319 Pt 3 117338 10.1016/j.jep.2023.117338 37890804
    [Google Scholar]
  35. Shi H. Zhou J. Ma C. Ji F. Wu Y. Zhao Y. Qian J. Wang X. Shexiang baoxin pill (MUSKARDIA) reduces major adverse cardiovascular events in women with stable coronary artery disease: A subgroup analysis of a phase IV randomized clinical trial. Front. Cardiovasc. Med. 2022 9 1002400 10.3389/fcvm.2022.1002400 36386372
    [Google Scholar]
  36. Wei J. Leng L. Sui Y. Song S. Owusu F.B. Li X. Cao Y. Li P. Wang H. Li R. Yang W. Gao X. Wang Q. Phenolic acids from Prunella vulgaris alleviate cardiac remodeling following myocardial infarction partially by suppressing NLRP3 activation. Phytother. Res. 2024 38 1 384 399 10.1002/ptr.8024 37992723
    [Google Scholar]
  37. Zhang Z. Chen F. Wan J. Liu X. Potential traditional Chinese medicines with anti-inflammation in the prevention of heart failure following myocardial infarction. Chin. Med. 2023 18 1 28 10.1186/s13020‑023‑00732‑w 36932409
    [Google Scholar]
  38. Li C. Zhang Y. Wang Q. Meng H. Zhang Q. Wu Y. Xiao W. Wang Y. Tu P. Dragon’s Blood exerts cardio-protection against myocardial injury through PI3K-AKT-mTOR signaling pathway in acute myocardial infarction mice model. J. Ethnopharmacol. 2018 227 279 289 10.1016/j.jep.2018.09.010 30195568
    [Google Scholar]
  39. Liao J. Zhang Y. Ma C. Wu G. Zhang W. Microbiome-metabolome reveals that the Suxiao Jiuxin pill attenuates acute myocardial infarction associated with fatty acid metabolism. J. Ethnopharmacol. 2023 312 116529 10.1016/j.jep.2023.116529 37086873
    [Google Scholar]
  40. Li C. Du X. Liu Y. Liu Q.-Q. Zhi W.B. Wang C.L. Zhou J. Li Y. Zhang H. A systems pharmacology approach for identifying the multiple mechanisms of action for the Rougui-Fuzi herb pair in the treatment of cardiocerebral vascular diseases. Evid. Based Compl. Alternat. Med. 2020 2020 5196302 10.1155/2020/5196302
    [Google Scholar]
  41. Li C. Wang J. Wang Q. Zhang Y. Zhang N. Lu L. Wu Y. Zhang Q. Wang W. Wang Y. Tu P. Qishen granules inhibit myocardial inflammation injury through regulating arachidonic acid metabolism. Sci. Rep. 2016 6 1 36949 10.1038/srep36949 27833128
    [Google Scholar]
  42. Li Z. Xu S. Liu P. Salvia miltiorrhizaBurge (Danshen): A golden herbal medicine in cardiovascular therapeutics. Acta Pharmacol. Sin. 2018 39 5 802 824 10.1038/aps.2017.193 29698387
    [Google Scholar]
  43. Cheng T.O. Cardiovascular effects of Danshen. Int. J. Cardiol. 2007 121 1 9 22 10.1016/j.ijcard.2007.01.004 17363091
    [Google Scholar]
  44. Ren J. Fu L. Nile S.H. Zhang J. Kai G. Salvia miltiorrhiza in treating cardiovascular diseases: A review on its pharmacological and clinical applications. Front. Pharmacol. 2019 10 753 10.3389/fphar.2019.00753 31338034
    [Google Scholar]
  45. Wang S. Hu Y. Tan W. Wu X. Chen R. Cao J. Chen M. Wang Y. Compatibility art of traditional Chinese medicine: From the perspective of herb pairs. J. Ethnopharmacol. 2012 143 2 412 423 10.1016/j.jep.2012.07.033 22871585
    [Google Scholar]
  46. Li X. Wu L. Liu W. Jin Y. Chen Q. Wang L. Fan X. Li Z. Cheng Y. A network pharmacology study of Chinese medicine QiShenYiQi to reveal its underlying multi-compound, multi-target, multi-pathway mode of action. PLoS One 2014 9 5 e95004 10.1371/journal.pone.0095004 24817581
    [Google Scholar]
  47. Liang X. Chen X. Liang Q. Zhang H. Hu P. Wang Y. Luo G. Metabonomic study of Chinese medicine Shuanglong formula as an effective treatment for myocardial infarction in rats. J. Proteome Res. 2011 10 2 790 799 10.1021/pr1009299 21090666
    [Google Scholar]
  48. Chao J. Dai Y. Verpoorte R. Lam W. Cheng Y.C. Pao L.H. Zhang W. Chen S. Major achievements of evidence-based traditional Chinese medicine in treating major diseases. Biochem. Pharmacol. 2017 139 94 104 10.1016/j.bcp.2017.06.123 28636884
    [Google Scholar]
  49. Yang R. Liu A. Ma X. Li L. Su D. Liu J. Sodium tanshinone IIA sulfonate protects cardiomyocytes against oxidative stress-mediated apoptosis through inhibiting JNK activation. J. Cardiovasc. Pharmacol. 2008 51 4 396 401 10.1097/FJC.0b013e3181671439 18427283
    [Google Scholar]
  50. Ibánez B. James S. Agewall S. Antunes M.J. Ducci B.C. Bueno H. Caforio A.L.P. Crea F. Goudevenos J.A. Halvorsen S. Hindricks G. Kastrati A. Lenzen M.J. Prescott E. Roffi M. Valgimigli M. Varenhorst C. Vranckx P. Widimský P. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Rev. Esp. Cardiol. 2017 70 12 1082 10.1016/j.rec.2017.11.010 29198432
    [Google Scholar]
  51. Li X. Zhang J. Huang J. Ma A. Yang J. Li W. Wu Z. Yao C. Zhang Y. Yao W. Zhang B. Gao R. Multicenter A. A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure. J. Am. Coll. Cardiol. 2013 62 12 1065 1072 10.1016/j.jacc.2013.05.035 23747768
    [Google Scholar]
  52. Ong S.B. Reséndiz H.S. Avilan C.G.E. Mukhametshina R.T. Kwek X.Y. Fuentes C.H.A. Hausenloy D.J. Inflammation following acute myocardial infarction: Multiple players, dynamic roles, and novel therapeutic opportunities. Pharmacol. Ther. 2018 186 73 87 10.1016/j.pharmthera.2018.01.001 29330085
    [Google Scholar]
  53. Zhao D. Liu J. Wang M. Zhang X. Zhou M. Epidemiology of cardiovascular disease in China: Current features and implications. Nat. Rev. Cardiol. 2019 16 4 203 212 10.1038/s41569‑018‑0119‑4 30467329
    [Google Scholar]
  54. Cheng S. Zhang X. Feng Q. Chen J. Shen L. Yu P. Yang L. Chen D. Zhang H. Sun W. Chen X. Astragaloside IV exerts angiogenesis and cardioprotection after myocardial infarction via regulating PTEN/PI3K/Akt signaling pathway. Life Sci. 2019 227 82 93 10.1016/j.lfs.2019.04.040 31004658
    [Google Scholar]
  55. Han A. Lu Y. Zheng Q. Zhang J. Zhao Y. Zhao M. Cui X. Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction. Cell. Physiol. Biochem. 2018 45 5 1797 1806 10.1159/000487871 29510381
    [Google Scholar]
  56. Roth G.A. Johnson C. Abajobir A. Allah A.F. Abera S.F. Abyu G. Ahmed M. Aksut B. Alam T. Alam K. Alla F. Guzman A.N. Amrock S. Ansari H. Ärnlöv J. Asayesh H. Atey T.M. Burgos A.L. Awasthi A. Banerjee A. Barac A. Bärnighausen T. Barregard L. Bedi N. Ketema B.E. Bennett D. Berhe G. Bhutta Z. Bitew S. Carapetis J. Carrero J.J. Malta D.C. Orjuela C.C.A. Rivas C.J. López C.F. Choi J.Y. Christensen H. Cirillo M. Cooper L. Jr Criqui M. Cundiff D. Damasceno A. Dandona L. Dandona R. Davletov K. Dharmaratne S. Dorairaj P. Dubey M. Ehrenkranz R. El Sayed Zaki M. Faraon E.J.A. Esteghamati A. Farid T. Farvid M. Feigin V. Ding E.L. Fowkes G. Gebrehiwot T. Gillum R. Gold A. Gona P. Gupta R. Habtewold T.D. Nejad H.N. Hailu T. Hailu G.B. Hankey G. Hassen H.Y. Abate K.H. Havmoeller R. Hay S.I. Horino M. Hotez P.J. Jacobsen K. James S. Javanbakht M. Jeemon P. John D. Jonas J. Kalkonde Y. Karimkhani C. Kasaeian A. Khader Y. Khan A. Khang Y.H. Khera S. Khoja A.T. Khubchandani J. Kim D. Kolte D. Kosen S. Krohn K.J. Kumar G.A. Kwan G.F. Lal D.K. Larsson A. Linn S. Lopez A. Lotufo P.A. Razek E.H.M.A. Malekzadeh R. Mazidi M. Meier T. Meles K.G. Mensah G. Meretoja A. Mezgebe H. Miller T. Mirrakhimov E. Mohammed S. Moran A.E. Musa K.I. Narula J. Neal B. Ngalesoni F. Nguyen G. Obermeyer C.M. Owolabi M. Patton G. Pedro J. Qato D. Qorbani M. Rahimi K. Rai R.K. Rawaf S. Ribeiro A. Safiri S. Salomon J.A. Santos I. Milicevic S.M. Sartorius B. Schutte A. Sepanlou S. Shaikh M.A. Shin M.J. Shishehbor M. Shore H. Silva D.A.S. Sobngwi E. Stranges S. Swaminathan S. Seisdedos T.R. Atnafu T.N. Tesfay F. Thakur J.S. Thrift A. Madry T.R. Truelsen T. Tyrovolas S. Ukwaja K.N. Uthman O. Vasankari T. Vlassov V. Vollset S.E. Wakayo T. Watkins D. Weintraub R. Werdecker A. Westerman R. Wiysonge C.S. Wolfe C. Workicho A. Xu G. Yano Y. Yip P. Yonemoto N. Younis M. Yu C. Vos T. Naghavi M. Murray C. Global, regional, and national burden of cardiovascular diseases for 10 causes, 1990 to 2015. J. Am. Coll. Cardiol. 2017 70 1 1 25 10.1016/j.jacc.2017.04.052 28527533
    [Google Scholar]
  57. Jiang B. Wu W. Li M. Xu L. Sun K. Yang M. Guan S. Liu X. Guo D. Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats. Planta Med. 2009 75 12 1286 1292 10.1055/s‑0029‑1185669 19431100
    [Google Scholar]
  58. Jiang P. Dai W. Yan S. Chen Z. Xu R. Ding J. Xiang L. Wang S. Liu R. Zhang W. Biomarkers in the early period of acute myocardial infarction in rat serum and protective effects of Shexiang Baoxin Pill using a metabolomic method. J. Ethnopharmacol. 2011 138 2 530 536 10.1016/j.jep.2011.09.049 22001859
    [Google Scholar]
  59. Zhang X. Wang Q. Wang X. Chen X. Shao M. Zhang Q. Guo D. Wu Y. Li C. Wang W. Wang Y. Tanshinone IIA protects against heart failure post-myocardial infarction via AMPKs/mTOR-dependent autophagy pathway. Biomed. Pharmacother. 2019 112 108599 10.1016/j.biopha.2019.108599 30798134
    [Google Scholar]
  60. Li H. Zhu J. Xu Y. Mou F. Shan X. Wang Q. Liu B. Ning K. Liu J. Wang Y. Mi J. Wei X. Shao S. Cui G. Lu R. Guo H. Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction. Redox Biol. 2022 54 102384 10.1016/j.redox.2022.102384 35777198
    [Google Scholar]
  61. Wang H. Xie B. Shi S. Zhang R. Liang Q. Liu Z. Cheng Y. Curdione inhibits ferroptosis in isoprenaline-induced myocardial infarction via regulating Keap1 / Trx1 / GPX4 signaling pathway. Phytother. Res. 2023 37 11 5328 5340 10.1002/ptr.7964 37500597
    [Google Scholar]
  62. Jia D. Zhang C. Qiu Y. Chen X. Jia L. Chen A.F. Chai Y. Zhu Z. Huang J. Zhang C. Cardioprotective mechanisms of salvianic acid A sodium in rats with myocardial infarction based on proteome and transcriptome analysis. Acta Pharmacol. Sin. 2019 40 12 1513 1522 10.1038/s41401‑019‑0265‑1 31253938
    [Google Scholar]
  63. Boezio B. Audouze K. Ducrot P. Taboureau O. Network-based approaches in pharmacology. Mol. Inform. 2017 36 10 1700048 10.1002/minf.201700048 28692140
    [Google Scholar]
  64. Yang H.Y. Liu M.L. Luo P. Yao X.S. Zhou H. Network pharmacology provides a systematic approach to understanding the treatment of ischemic heart diseases with traditional Chinese medicine. Phytomedicine 2022 104 154268 10.1016/j.phymed.2022.154268 35777118
    [Google Scholar]
  65. Liang D. Yixuan D. Chang L. Jingjing S. Sihai Z. Jie D. Mechanism of Artemisia annua L. in the treatment of acute myocardial infarction: Network pharmacology, molecular docking and in vivo validation. Mol. Divers. 2024 28 5 3225 3242 10.1007/s11030‑023‑10750‑3 37898972
    [Google Scholar]
  66. Wan J. Zhang Z. Wu C. Tian S. Zang Y. Jin G. Sun Q. Wang P. Luan X. Yang Y. Zhan X. Ye L.L. Duan D.D. Liu X. Zhang W. Astragaloside IV derivative HHQ16 ameliorates infarction-induced hypertrophy and heart failure through degradation of lncRNA4012/9456. Signal Transduct. Target. Ther. 2023 8 1 414 10.1038/s41392‑023‑01660‑9 37857609
    [Google Scholar]
  67. Du C.S. Yang R-F. Song S-W. Wang Y-P. Kang J-H. Zhang R. Su D-F. Xie X. Magnesium lithospermate B protects cardiomyocytes from ischemic injury via inhibition of TAB1-p38 apoptosis signaling. Front. Pharmacol. 2010 1 111 10.3389/fphar.2010.00111 21607062
    [Google Scholar]
  68. Tan D. Wu J. Zhang X. Liu S. Zhang B. Sodium tanshinone II a sulfonate injection as adjuvant treatment for unstable angina pectoris: A meta-analysis of 17 randomized controlled trials. Chin. J. Integr. Med. 2018 24 2 156 160 10.1007/s11655‑017‑2424‑x 29181731
    [Google Scholar]
  69. Pan J. Wang J. Lei Z. Wang H. Zeng N. Zou J. Zhang X. Sun J. Guo D. Luan F. Shi Y. Therapeutic potential of chinese herbal medicine and underlying mechanism for the treatment of myocardial infarction. Phytother. Res. 2024 ptr 8368 10.1002/ptr.8368
    [Google Scholar]
  70. Boarescu P.M. Boarescu I. Bocșan I.C. Gheban D. Bulboacă A.E. Nicula C. Pop R.M. Râjnoveanu R.M. Bolboacă S.D. Antioxidant and anti-inflammatory effects of curcumin nanoparticles on drug-induced acute myocardial infarction in diabetic rats. Antioxidants 2019 8 10 504 10.3390/antiox8100504 31652638
    [Google Scholar]
  71. Mu L. Dong R. Li C. Chen J. Huang Y. Li T. Guo B. ROS responsive conductive microspheres loaded with salvianolic acid B as adipose derived stem cell carriers for acute myocardial infarction treatment. Biomaterials 2025 314 122849 10.1016/j.biomaterials.2024.122849 39357150
    [Google Scholar]
  72. Xiang M. Zhao X. Lu Y. Zhang Y. Ding F. Lv L. Wang Y. Shen Z. Li L. Cui X. Modified linggui zhugan decoction protects against ventricular remodeling through ameliorating mitochondrial damage in post-myocardial infarction rats. Front. Cardiovasc. Med. 2023 9 1038523 10.3389/fcvm.2022.1038523 36704451
    [Google Scholar]
/content/journals/cmc/10.2174/0109298673362741250128065027
Loading
/content/journals/cmc/10.2174/0109298673362741250128065027
Loading

Data & Media loading...

Supplements

Supplementary material is available on the publisher's website along with the published article.


  • Article Type:
    Research Article
Keywords: CiteSpace ; myocardial infarction ; VOSviewer ; Traditional chinese medicine ; bibliometric
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test