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2000
Volume 20, Issue 6
  • ISSN: 1573-3998
  • E-ISSN: 1875-6417

Abstract

Background: Vitamin D deficiency is becoming a widely recognized global health issue. Serum values of 25-(OH) vitamin D (<20 ng/ml) are used to identify vitamin D deficiency. By prompting vascular endothelial cells to activate their nuclear receptor in cardio-myocytes, Vitamin D regulates obesity, Renin-angiotensin system (RAS), energy consumption, and pancreatic cell function. Vitamin D deficiency has been associated with diabetes, asthma, hyperlipidaemia, and pulmonary hypertension in humans. Methods: PubMed and Google Scholar databases were utilised to search the literature on vitamin D and related diseases. Result: It is also linked to an elevated risk of death and heart disease. On the other hand, metaanalyses of vitamin D intervention and trials have found no substantial changes in insulin sensitivity, lipid markers, or blood pressure, which result in the association between deficiency of vitamin D and cardiovascular disease. Conclusion: In this review, we present the most recent research on the effects of Vitamin D therapy on various cardiovascular diseases and diabetes, and explain the underlying mechanisms.

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/content/journals/cdr/10.2174/1573399820666230901151019
2024-07-01
2024-12-25
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/content/journals/cdr/10.2174/1573399820666230901151019
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