Current Drug Delivery - Volume 19, Issue 2, 2022

Unprincipled use of antibiotics has led to antimicrobial resistance (AMR) against mostly available compounds, and has now become a major cause of concern for the scientific community. However, in the past decade, green synthesized silver nanoparticles (AgNPs) have received greater attention for the development of newer therapies as antimicrobials by virtue of their unique physico- chemical properties. Unlike traditio Read More

Polyphenols comprise a large group of naturally occurring plant secondary metabolites with various nutritional and health benefits. They are safe and are found abundantly in the diet. Current research on polyphenols focuses on their mechanism and their benefits on human health. However, due to their low solubility and bioavailability, delivery from the conventional route has been a challenge and their translation into clinical Read More

Wound healing is a complex and dynamic phenomenon that involves the restoration of normal physiology and functioning of injured tissue. The process of wound healing is primarily regulated by various cytokines, inflammatory mediators, and growth factors at the molecular level. Any intervention in the normal wound healing process leads to further tissue damage, which in turn leads to delayed wound healing. Several Read More

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases reported in the aging population across the globe. About 46.8 million people are reported to have dementia, and AD is mainly responsible for dementia in aged people. Alzheimer's disease (AD) is thought to occur due to the accumulation of β-amyloid (Aβ) in the neocortex portion of the brain, nitric oxide mediated dysfunctioning of blood-brai Read More

At present, treatment methods for cancer are limited, partially due to the solubility, poor cellular distribution of drug molecules and the incapability of drugs to cross the cellular barriers. Carbon Nanotubes (CNTs) generally have excellent physio-chemical properties, which include High-level penetration into the cell membrane, high surface area, and high capacity of drug-loading by circulating modification with biomolecules, Read More

Purpose: Gastric absorption is an upfront route for drug delivery as it is convenient, economical and most suitable for getting the desired systemic effects. Unfortunately, many traditional and newer generation drugs suffer from poor solubility and have lower bioavailability. With a perspective of bringing a novel delivery system in such a condition for old/existing/new drugs, liquidfilled hard capsules hold promise as the delivery sys Read More