Current Chinese Science - Volume 2, Issue 4, 2022

Background: Psoralea corylifolia L. is an important herbal medicine mainly used for the treatment of coronary artery disease, osteoporosis, bacterial infections, vitiligo, and psoriasis. P. corylifolia contains numerous active phytochemicals, including bavachalcone. Polyphenolic compounds, including flavonoidal class phytochemicals, are secondary plant metabolites found in numerous plant species and reported to have multi Read More

Micellar nanoparticles synthesized through the self-assembly of amphiphilic copolymers have been widely used to encapsulate various cancer therapeutic agents for preclinical and clinical applications. These drug delivery systems are easy to fabricate and have good biocompatibility in general. In this article, we provide an overview of the advantages and disadvantages of micellar nanoparticles for the fabrication of ther Read More

Platinum-based drugs have been proved to be one of the prevalent successes in the field of inorganic medicinal chemistry. So far, three generations of platinum-based drugs are on the market and are recognized to play critical roles in the treatment of various types of tumors. The most commonly used anticancer chemotherapeutics worldwide are cisplatin, oxaliplatin, and carboplatin. They are known to exhibit pro Read More

Aim: The black market for Remdesivir for the treatment of COVID-19 is surging in the world. This condition leads to the uprising of drugs from the common hospital inventory, of which Dexamethasone is an effective weapon to be employed against the coronavirus. Background: Remdesivir is an intravenous nucleotide prodrug of an adenosine analog. Dexamethasone was tested in hospitalized patients with COVID-19 in the UK’s n Read More

In magnetic molecular junctions, the interactions between the local spin state at the transition- metal center and the conduction electrons from the electrodes or substrates can bring about many interesting strong correlation effects. Spin excitation and the Kondo effect are two representative phenomena, where the spin-unpaired d or f electrons plays the key role in forming these manybody states. This paper reviews the recen Read More

Background: The H2O-Ar system has attracted significant interest in recent years because it is an important model to study inelastic scattering between atoms and triatomic molecules. A high-accuracy intermolecular potential energy surface (IPES) is the foundation for theoretical study on molecular collision dynamics for H2O-Ar. In addition, dipole moment surfaces (DMSs) are one of the prerequisites for spectral simulation Read More