Skip to content
2000
Volume 16, Issue 10
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

A simple, clean and rapid one-pot three component, microwave-assisted synthesis of pyrrolo[1,2-c]pyrimidine derivatives starting from various substituted pyrimidines, 2-bromoacetophenones and nonsymmetrical, electron deficient alkynes in 1,2-epoxybutane which acts both as solvent and acid scavenger is reported. This one-pot three component synthesis implies short reaction times being at the same time highly cost-effective and environmental friendly.

Loading

Article metrics loading...

/content/journals/cchts/10.2174/13862073113169990050
2013-12-01
2025-07-08
Loading full text...

Full text loading...

/content/journals/cchts/10.2174/13862073113169990050
Loading

  • Article Type:
    Research Article
Keyword(s): 1; 2-c]pyrimidine; 3-dipolar cycloaddition; microwaves; multicomponent reaction; N-ylide; pyrrolo
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test