Stability and Drug Metabolism Assessed by Electrochemical Methods

Alejandro Alvarez-Lueje; Soledad Bollo Dragnic

doi:10.2174/138620710791920329

ISSN: 1386-2073
E-ISSN: 1875-5402

Stability and Drug Metabolism Assessed by Electrochemical Methods
Authors: Alejandro Alvarez-Lueje¹ and Soledad Bollo Dragnic²
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¹ Bioelectrochemistry Laboratory, Chemical and Pharmaceutical Sciences Faculty, University of Chile, P.O. Box 233, Santiago 1, Chile. ² Bioelectrochemistry Laboratory, Chemical and Pharmaceutical Sciences Faculty, University of Chile, P.O. Box 233, Santiago 1, Chile.
Source: Combinatorial Chemistry & High Throughput Screening, Volume 13, Issue 8, Sep 2010, p. 712 - 727
DOI: https://doi.org/10.2174/138620710791920329
- Available online: 01 Sep 2010

Abstract

This review is focused on the use of the electrochemical techniques, voltammetry and polarography, as well as biosensors, for the study of drug stability. In addition, this review also details the study of drug metabolism by electrochemistry and mass spectrometry. This is used as a tool to mimic drug metabolism and because it is a purely instrumental method, may have advantages over, or be complementary to, the existing biological assays.

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2010-09-01

2025-04-16

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Article Type: Research Article

Keyword(s): biosensors; Drug; electrochemistry-mass spectrometry; metabolism; polarography; stability; voltammetry

Stability and Drug Metabolism Assessed by Electrochemical Methods

Abstract

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