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2000
Volume 13, Issue 7
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

A sensitive aptamer based electrochemical biosensor to detect human immunoglobulin E (IgE) is presented in this study. 5' Biotin labeled 45 mer DNA aptamer sequence was immobilized onto streptavidin coated graphite surfaces. Interaction between human IgE and DNA aptamer was monitored by Electrochemical Impedance Spectrometry (EIS) in a 0.48nM detection limit of IgE. EIS analyses are based on electron transfer resistance (Rct) in the presence of 5mM [Fe(CN)6]3-/4-.

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/content/journals/cchts/10.2174/138620710791601279
2010-08-01
2025-07-06
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/content/journals/cchts/10.2174/138620710791601279
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  • Article Type:
    Research Article
Keyword(s): Aptamer; biosensor; electrochemical impedance spectrometry (EIS); IgE
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