Clinical Cancer Drugs - Current Issue

In recent years, there has been a notable increase in the global incidence of oral cancer, leading to significant morbidity and mortality, especially when diagnosed at advanced stages. The integration of technology holds great promise for early detection and diagnosis, facilitating improved patient management for clinicians. The emergence of artificial intelligence (AI) presents a potential breakthrough in oral cancer screeni Read More

Colorectal cancer (CRC) is the third most commonly occurring cancer and the second leading cause of cancer-related deaths worldwide. Conventional treatments for CRC, such as surgery, chemotherapy, and radiotherapy, have long been the primary options for patients. However, their therapeutic success rates are relatively low, necessitating the development of novel technologies. The prognosis for metastatic CR Read More

BackgroundCyclooxygenase-2 (COX-2) is induced in response to proinflammatory conditions, and it is not only a key enzyme in the inflammatory process, but also seems to be highly expressed in various types of cancer cells. On the other hand, it is well documented that chemical compounds with spiro scaffolds in their structure could be effective chemical agents against cancer types.ObjectiveIn this study, the cytotoxicity effe Read More