Current Biotechnology - Volume 12, Issue 1, 2023

In order to tackle multifactorial illnesses, the importance of bioactive peptides in nano drug delivery systems is emphasised. Multifactorial diseases are primarily brought on by protein misfolding. Therefore, pharmaceutical formulations are recommended to deliver a successful treatment. Difficulties hinder its application in delivering raw peptides with poor bioavailability, absorption, and circulation time, making it a difficult Read More

The coronavirus pandemic hit the world with different variants of SARS-CoV-2; reliable therapeutics are needed every hour to control and minimize the infection. To date, the way to menace the chaos of post-COVID infection is not confined rationally. Researchers are still on their way to the progression of an efficient way to eradicate the disease. However, to prevent it from causing infection post-entry into the body, there ha Read More

Lipases are carboxylic ester hydrolase enzymes, constituting the class of serine hydrolases, requiring no cofactor for their action. They have various substrates and produce glycerol and free fatty acids through the hydrolysis of fats and oils. Owing to their wide applications and the simplicity with which they can be mass-produced, these are a significant group of biotechnologically important enzymes. In addition, lipa Read More

Background: Determination of glucose is crucial in chemical, biological, and clinical samples, food processing, and fermentation. Despite 50 years of reports on biosensor technology development, it is still important to research new glucose biosensors. Objective: The main purpose of this study is to design and build a simple and effective glucose biosensor based on Citrullus Colocynthis and Urtica Dioica. Methods: In this study, th Read More

Background: Yeasts with high protein content are used as single-cell proteins due to their nutritional values and rare pathogenicity. However, the nucleic acid of the yeasts must be removed before consumption to avoid hazards to health. Wickerhamomyces anomalus is an authorized bio-preservative with promising antifungal activity and safety. However, its high protein content associated with high nucleic acid content re Read More

Background: The bile concretions formed inside the gallbladder are called gallstones. Gallstone disease is one of the major causes of morbidity, mortality, and economic burden throughout the world. Approximately 10% to 20% of the world population and 4.87% in Nepal are suffering from a gallstone. Objective: The aim is to classify the gallstone samples based on morphological and cross-sectional evidences, and a comparat Read More