
Full text loading...
2-Cyanoethanethioamide (1) reacted with α,β-unsaturated ketones 2a,b to afford the corresponding 2- thioxopyridine-3-carbonitrile derivatives 6a,b. The reactivity of the latter products towards various chemical reagents was studied to yield both thieno[2,3-b]pyridines 9a-r and 3-aminothieno[2,3-b]pyridine-2-carbohydrazides 10a,b which were used in turn, to prepare N-phenylmethylenethieno[2,3-b]pyridine-2-carbohydrazides 13a,bpyrido[3',2':4,5]thieno[3,2- d]pyrimidinones (15a,b,16a,b) and pyrido[3',2':4,5]thieno[3,2-d]triazinones 17a,b. Considering the data of IR,1H NMR, mass spectra and elemental analyses the chemical structures of the newly synthesized heterocyclic compounds were elucidated.