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2000
Volume 8, Issue 2
  • ISSN: 1573-4072
  • E-ISSN: 1875-6646

Abstract

2-Cyanoethanethioamide (1) reacted with α,β-unsaturated ketones 2a,b to afford the corresponding 2- thioxopyridine-3-carbonitrile derivatives 6a,b. The reactivity of the latter products towards various chemical reagents was studied to yield both thieno[2,3-b]pyridines 9a-r and 3-aminothieno[2,3-b]pyridine-2-carbohydrazides 10a,b which were used in turn, to prepare N-phenylmethylenethieno[2,3-b]pyridine-2-carbohydrazides 13a,bpyrido[3',2':4,5]thieno[3,2- d]pyrimidinones (15a,b,16a,b) and pyrido[3',2':4,5]thieno[3,2-d]triazinones 17a,b. Considering the data of IR,1H NMR, mass spectra and elemental analyses the chemical structures of the newly synthesized heterocyclic compounds were elucidated.

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/content/journals/cbc/10.2174/157340712801784769
2012-06-01
2025-05-04
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