Current Aging Science - Volume 14, Issue 3, 2021

It is established that the gut microbiota has a significant influence on Alzheimer’s disease. In turn, both the disease and the microbiota are affected by biological variables associated with modern lifestyles. Examination of the potential interrelationship among these three factors and on the role played by lifestyles in gut dysbiosis-induced pathologies of Alzheimer’s disease are limited. Deciphering these connections will provide in Read More

Background: Currently, the focus of anti-aging research has been changed from geriatrics to biogerontology. This has taken anti-aging strategies from cost-effective but palliative therapeutics to active, molecular approaches. Outline: Over the years, a large body of basic gerontological research has indicated that the process of biological aging is closely associated with genetic factors. This leads to the development of va Read More

Background: Since age is the major risk factor for chronic diseases and mortality, it seems mistaken that older adults have lower basal temperature than young individuals. Many confounding factors could hinder the achievement of a consensus, such as the different sites of measurement, control of basal conditions, health conditions, age difference compared, sex, and others. Objective: The aim was to meta-analyze previous studi Read More

Aims: The aim of the study was to assess the activation of prefrontal cortex during sustained attention task in young and middle aged adults using Functional near infrared spectroscopy system. Background: Sustained Attention (SA) is a construct of cognition that tends to decline with age. There is a paucity of literature regarding the neural correlates of SA in middle age, a link between young and old age. Objective: This stu Read More

Background: A relationship between body size and longevity has long been appreciated within eukaryotes, especially vertebrates. Introduction: In general, the large size is associated with increased longevity among species of mammals and birds but is associated with decreased longevity within individual species such as dogs and mice. In this study, we examined the relationship between measures of individual body size an Read More

Aims: Lipoprotein (a) deposition in coronary vascular plaques and cerebral vessels is a recognized risk factor for cardiovascular disease, and research supports its role as a “repair factor” in vascular walls weakened by vitamin C deficiency. Background: Humans depend on dietary vitamin C as an important antioxidant and as a cofactor in collagen synthesis, yet are prone to vitamin C deficiency. The brain is the one with the Read More

Background: Age is related to a decline in muscle mass and physical function in both respiratory and peripheral muscle strength, which could lead to mobility and mortality. In addition, older people have suffered from one or multiple chronic conditions in particular in type 2 Diabetes Mellitus (type 2 DM). However, a few studies have reported the relationship between sarcopenic elderly and respiratory and peripheral muscle st Read More

Background: The use of symptomatic slow-acting drugs for osteoarthritis (OA) (e.g., glucosamine, chondroitin) is largely debated in the scientific literature. Indeed, multiple formulations of these agents are available, both as pharmaceutical-grade products and as nutritional supplements , but while all preparations may claim to deliver a therapeutic effect, not all are supported by clinical evidence. Moreover, few data are availa Read More