Current Analytical Chemistry - Volume 12, Issue 5, 2016

Background: Nucleic acid amplification test (NAAT) provides the highest levels of sensitivity and specificity for sequence-specific detection of DNA and RNA associated with pathogens and diseases. Currently, these tests are largely limited to laboratory use, as they require considerable sample preparation and expensive instrumentation. However, emerging microfluidic lab-on-a-chip technology enables lowcost, easy-to-use, pal Read More

Mild and efficient synthetic procedures were developed for the preparation of a series of adenine, thymine and uracil-derivatives in high yields. In this respect, four derivatives were derived by introducing various substituents flanked by two methylene groups at the 1- and 9- positions of pyrimidine and purine bases, respectively. The other two were prepared from 6-amino-1,3-dimethyluracil or 5,6-diamino- 1,3-dimethylur Read More

In the present study, an on-line preconcentration system for the determination of Cd and Zn was developed. This system involves solid-phase extraction of metals using a minicolumn filled with Amberlite XAD-2 modified with 2-(5-bromo-2- pyridylazo)-5-diethylaminophenol (Br-PADAP) and detected by flame atomic absorption spectrometry (FAAS). After the preconcentration step, hydrochloric acid was used in the elution pr Read More

The purpose of this paper is to develop a new method for determining total antioxidants capacity (TAC) in urine. In our study, Na2S2O3 and mixed urine were used to evaluate the linearity and precision of the iodine starch agar method. The areas of urine diffusion in samples from 44 coronary heart disease patients and 44 healthy subjects were determined by the iodine starch agar method. The results have shown that the line Read More

Background: Considering that BPA has emerged as a major public health issue, there is an urgent need to establish a simple, effective, and highly sensitive method for monitoring the levels of BPA. The aim of this work was to construct an electrochemical sensor for the detection of BPA by the combination of molecularly imprinted technique and MWCNTs. The optimization of test conditions and the performance of the imprinted Read More

Diketopiperazines (DKPs) are cyclic dipeptides which have been detected in a variety of natural products, especially in thermally treated or fermented foods and beverages, providing a metallic bitter taste. DKPs, mainly due to their characteristic heterocyclic system, have been reported to exhibit a broad spectrum of biological activities including antimicrobial, antiviral, antitumor, antihyperglycaemic and antimutagenic. D Read More

Background: Nicotine is the main tobacco alkaloid that leads to smoking addiction. Human serum albumin (HSA) is the most abundant protein present in the circulatory system. Nuclear magnetic resonance (NMR) has been widely used for studying the interactions of small molecules with macromolecules. The proton spin relaxation rate of the small molecule has proved to be a suitable parameter in ligand– macromolecule Read More

Background: In this work, the chemical polymerization of P-NPhPy on the polyester fibers in the mixed solution of sodium dodecyl benzene sulphonate (SDBS) with FeCl3 by chemical method is reported. A new SPME syringe suitable for fabricated fiber is designed and used to extract some VOCs from water samples and analysis by GC-FID. In fact the purpose of this paper was the presentation of a new chemically synt Read More

Dyes represent an extreme environmental hazard and are extensively found in the waste water of industrial discharges. Therefore, the fabrication of an effective photocatalyst for the degradation of pollutants is necessary. In this work, the photocatalytic degradation of methyl orange (MO) in aqueous solution under UV light irradiation was investigated using zinc oxide (ZnO) nanoparticles that were chemically prepared by the s Read More

Background: Corrosion in industrial structures has generated much concern with regard to material loss, especially in the oil production. Organicmolecules can act as inhibitors because they can be adsorbed at the metal-solution interface, replacing the water molecules and thereby inhibiting the metal dissolution. In general the imidazoline derivatives have unique structure that make them efficient corrosion inhibitors Read More

New hollow fiber based liquid phase microextraction (HF-LPME) technique followed by high performance liquid chromatography (HPLC) coupled with ultraviolet (UV) detector was introduced for detection and determination of terazosin in urine and plasma samples. The effect of different parameters which influence extraction efficiency such as organic membrane solvent, donor/acceptor phase composition, extraction tim Read More

The constituents of the essential oil of Orobanche alba Stephan growing wild in Iran using GC-FID and GC-MS were identified. Forty components were identified, constituting approximately 96.09% of the oil. The oil was rich in Geranyl acetate (26.0%), Palmitic acid (12.5%), Geranial (11.8%) and Neral (10.2%). The results obtained showed that the essential oil of O. alba Stephan consists of twelve oxygenated monoterpene co Read More

Background: Polymer based adsorbents and their modified forms by various ligands have been effectively used for separation, preconcentration, determination and removal of heavy metal ions from different matrices. This paper proposes a solid phase extraction method based on 5-amino-1,10-phenanthroline (5-Aphen) functionalized glycidyl methacrylate-methyl methacrylate-divinylbenzene (GMA-MMA-DVB) crosslinked-po Read More