Current Analytical Chemistry - Volume 11, Issue 4, 2015

In this paper, platinum nanoclusters (PtNCs) were synthesized by less sophisticated equipments with low cost and tedious procedures, and then applied to construct a simple electrochemical hydrazine sensor rapidly within the applied potential. PtNCs were proved to have advantages over platinum nanoparticles (PtNPs) in modifying glassy carbon electrode (GCE) for electrochemical and sensing applications. The sensor’s el Read More

The rapid development of the analytical instrumentation, used in routine analysis tests in both laboratory and industrial scale, has been accompanied by the application of different smart software. Such combinations are recommended since they are inexpensive while at the same time they can readily ensure reliable results in short timeframe. The present work is an attempt to provide simple solutions in difficult an Read More

A novel PVC-incorporated membrane electrode selective for iron(III) is described. The sensor is based on the use of novel tris(aminophenolate) sensing molecule Cis,cis-1,3,5-tris{(2- hydroxybenzyl)aminomethyl}cyclohexane (THAC, L). The optimized membrane containing THAC, PVC and o-nitrophenyloctyl ether in the ratio 4:33:63 exhibits the best performance by means of range of concentration (1.0x10-5 to 1.0x10-1M), sl Read More

Screening bioactive constituents from herbal medicines or traditional Chinese medicines according to traditional phytochemical approach is time-consuming and laborious. The objective of the present study is to provide a strategy for rapid screening of active candidates from plant extract based on the Quantitative Patteren-Activity Relationship. The chromatographic fingerprint (Patteren) data sets were obtained by our pre Read More

A new HPLC method have been developed and validated for simultaneous determination of carprofen, vitamin B1, B6 and B12 in veterinary pharmaceutical preparations medicines. The method used a Hypersil GOLD aQ (250 x 4.6 mm, 5 μm) column, under the following chromatographic conditions: gradient elution, using a mobile phase composed by phosphate buffer (pH 2.65) and methanol as an organic modifier. The m Read More

A multi-functional “turn-off” fluorescent probe, N-[[(6-Amino-1,2,3,4-tetrahydro-1,3- dimethyl-2,4-dioxo-5-pyrimidinyl)amino]thioxomethyl]- benzamide, was synthesized and characterized. The probe showed high sensitivity and selectivity towards copper(II), iron(III) and silver(I) ions via quenching of its fluorescence. The detection limits were found to be 4.0 – 16.0 ppb for the assayed cations. The thiourea linked uracil flu Read More

New materials - silica-titania xerogels modified with polyphenols (caffeic acid, catechol, and quercetin) or hydrogen peroxide - have been used for solid phase spectrophotometric determination of fluoride ions. The fast and simple method is based on the xerogel incorporated titanium(IV) complexes discoloration in the presence of fluoride ions. Parameters, such as modifying reagent nature pH, and time of contact, affectin Read More

In this study, we demonstrated an oxidative method with free radical to generate 3,5,4´-trihydroxy-transstilbene (trans-resveratrol) metabolites and detect sequentially by an autosampler coupling with liquid chromatography electrospray ionization tandem mass spectrometer (LC-ESI–MS/MS). In this oxidative method, the free radical initiator, ammonium persulfate (APS), was placed in a sample bottle containing resver Read More

Electrochemical sensors based on molecularly imprinted polymer (MIP) have attracted great attention over the past ten years. Among the strategies for the preparation of MIP modified electrode, electropolymerization is a potential technique, which can deposit a MIP film with special selectivity on the surface of the detector. In this work, the recent development of molecular imprinted electrochemical sensors based o Read More