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Electrochemical redox compounds, which can interact or bind with different affinities to single and double stranded DNA and thus are referred to as electrochemical hybridization indicators, represent a powerful and, along with this, simple tool for electrochemical genetic analysis. In this paper, general tendencies and recent advances in this field, including the modes of DNA-redox indicators interactions, approaches for their electrochemical analysis, and applications in electrochemical DNA assays are overviewed. This is a critical mini-review with 122 references.