Recent Patents on Biotechnology - Volume 12, Issue 4, 2018

Background: Ecotins are serine protease inhibitors which are generally found in the periplasmic compartment. These inhibitors act on a wide range of serine proteases with different efficiencies. Actually, only few Ecotins were studied, and the main characterized proteins were derived from Escherichia coli. Functional studies of this latter protein allowed the development of numerous patents related to Ecotin relevant biotech Read More

Background: The waterborne or airborne radon causes carcinogenesis in the human bodies due to the continuous decay of α- and β- particles. The health risks related to radioactive radon instigate to develop an advanced technology for its removal from the environment. There are two standard techniques, such as aeration and activated carbon filtration, available for its removal. However, both of them face different tec Read More

Background: Lipid modification results in several benefits for the food industry, biotechnology advances and human health. Customizing bioactive lipids is very appealing because it improves the product's nutritional quality. Lipases are sustainable biocatalysts that can be reused, show selectivity towards substrates and reactions occur in mild conditions. Objectives: We aimed at systematically searching for patents deposited world Read More

Background: Carcinoembryonic Antigen (CEA) is a recommended prognostic marker in Colorectal Cancer (CRC) for tumor diagnosis and monitoring response to therapy. High CEA levels are specifically associated with CRC progression and increased levels of the marker are expected to fall following surgical treatment. Due to its role in CRC, CEA has also been explored as a target for cancer therapy and diagnosis approache Read More

Background: Serine proteases have long been recognized to play key roles in various physiological processes. However, their disequilibrium can be linked to several diseases. Taking into account their wide diversity and specificity, they have been actively investigated by many industrial, academic and pharmaceutical industries. Objective: This review aims to provide a concise analysis of the described serine proteases as well as the Read More

Background: Propolis is a resinous complex produced by Apis mellifera L. bees whose variety of pharmacological properties results from the complexity of its composition. In dentistry, propolis is used on the prevention of oral diseases such as dental caries and gingivitis. Prospective studies in intellectual property banks are important to increase market competitiveness and thus generate new products in the various r Read More