Natural Products for Targeting Acanthamoeba spp.

Pathogenic Acanthamoeba is responsible for causing serious eye and fatal brain infections. A successful prognosis remains elusive despite advances in chemotherapeutics and supportive care. Natural products of medicinal value remain a promising source for drug development due to their broad-spectrum antimicrobial activities. Herein, we discuss anti-Acanthamoebic properties of natural products originating from plants, marine, and microbial sources that could be exploited as a potential avenue for drug discovery against infections caused by Acanthamoeba.