Screening of Phytochemicals from Curcuma Longa for their Inhibitory Activity on SARS-CoV-2: An In-Silico Study

Introduction: Natural products or phytochemicals have always been useful as effective therapeutics providing the lead for rational drug discovery approaches in specific to anti-viral therapeutics. Methods: The ongoing pandemic caused by novel coronavirus has created a demand for effective therapeutics. Thus, to achieve the primary objective to search for effective anti-viral therapeutics, in silico screening of phytochemicals present in the extract of Curcuma longa (ex. Curcumin) has been planned. Results: The present work involves the evaluation of ADME properties and molecular docking studies. Conclusion: The application of rationalized drug discovery approaches to screen the diverse natural resources will speed up the anti-COVID drug discovery efforts and benefit the global community.