Skip to content
2000
Volume 7, Issue 1
  • ISSN: 1574-8871
  • E-ISSN: 1876-1038

Abstract

Paliperidone Palmitate is a long-acting intramuscular atypical antipsychotic drug indicated for the acute maintenance treatment of schizophrenia in adults. Its mechanism of action, like all other atypical agents, is attributed to the antagonism of brain dopamine D2 and serotonin 5-HT2A receptors. The pharmacodynamics, pharmacokinetics, and metabolism of paliperidone palmitate are reviewed. Current studies for clinical efficacy of paliperidone palmitate for both acute and maintenance treatment and adherence in adults with schizophrenia are discussed. Studies for safety and tolerability are also reviewed.

Loading

Article metrics loading...

/content/journals/rrct/10.2174/157488712799363307
2012-02-01
2025-06-15
Loading full text...

Full text loading...

/content/journals/rrct/10.2174/157488712799363307
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test