Recent Patents on Regenerative Medicine - Volume 5, Issue 1, 2015

Cosmetic and reconstructive surgery relies extensively on the complex relationship between skin, soft tissue and the underlying bone skeleton. Soft tissue loss and acquired soft tissue deficits are some of the daily challenges faced by the plastic surgeon. Fat grafting has become one of the standard lines of care that has various applications in plastic surgery treatments. The ability of adipose stem cells to rejuvenate tissues i Read More

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron degeneration in the brain and spinal cord. Reliable treatment options for this disease are limited due to complexity and multifactorial causes of motor neuron damage. Cell therapy might be a promising treatment for ALS. Numerous preclinical studies have validated the feasibility of cell therapy using various cell typ Read More

Intellectual property rights are increasingly seen as critical to the survival and growth of new and emerging technologies, such as stem cell research. Breakthrough technologies are swiftly patented (i.e. WARF and Yamanaka) but not without ample obstacles. Too early in the research development and patents issued often overreach broadly and wreak havoc on any future scientific developments. In fact, the establish Read More

Human pluripotent stem cells in their characteristics of immortal self-renewal and pluripotency have gained high expectations during last fifteen years regarding their ability to cure near any human disease. Regenerative Medicine was the new term for the novel cell-based treatments, which had the possibility of curing genetic diseases as well by previous correction of endogenous mutations in patient-specific induced pluripot Read More

In recent years, cell-based therapies have gained great enthusiasm as a new therapeutic approach for addressing many disorders. Many researchers have shown the roles of stem cells in replacing damaged tissues and in providing extracellular factors that can promote endogenous cellular replenishment. Also, stem cells are rich source of soluble factors and microvesicles, which are released from their surfaces and Read More

Cancer stem cells (CSCs) are believed to cause cancer recurrence because they resist conventional therapies and restart the growth of tumor cells. CSCs has a specific biological behavior, mainly due to a deregulation of the self-renewal capacity. These cells differ in division and the cell cycle, replication capacity in DNA repair, and deregulation of signaling pathways. Collectively, these results give CSC a malignant phenotype. T Read More