Recent Patents on Regenerative Medicine - Volume 3, Issue 2, 2013

The placenta is a rich source of stem cells that can be easily isolated unencumbered by the ethical dilemmas of embryonic stem cells. There are a number of tissue banks across the world offering expectant parents the opportunity to harvest and store placenta, amniotic fluid and cord blood-derived stem cells. Consequently, the patent landscape surrounding the isolation, purification, expansion and use of such stem cells has Read More

Tendinitis is an important disease that leads to lameness and decreased performance in equine athletes and results in high costs associated with therapy due to a long recovery period and a high rate of recurrence. Although, several treatments for equine tendinitis have been described, few are effective in significantly improving the quality of the extracellular matrix and reducing the rate of recurrence. The use of cell therap Read More

Electronic pacemakers have succeeded in saving the lives of millions by providing medical palliation for cardiac conduction abnormalities. However, the caveats associated with usage of the same have prompted research in the development of a biological alternative which could replace or supplement its electronic counterpart. Biopacemaking could be done either by genetic engineering, cellular therapy or a combination of Read More

The multifunctional “adipose organ” is involved in thermal, metabolic and hormonal body balance. The high content of adult mesenchymal stem cells is recommending adipose tissue as an appealing reservoir of cells to be used in regenerative therapies. Adipose derived stem cells (ASC) have remarkable proliferative and differentiation potential. This paper reviews current scientific knowledge regarding the importance of ASC i Read More

Lameness secondary to chronic or acute injuries of the musculoskeletal system is a cause of equine wastage. This old problem has been traditionally managed with treatments, such as corticosteroids and non steroidal antiinflammatory drugs. However, recent discoveries in the pathophysiology of these diseases have provided new therapeutic approaches to their treatments. The stimulation of cellular proliferatio Read More

Nanotechnological modifiers of progenitor cells functions - immobilized (im) granulocyte colony stimulating factor (G-CSF) and hyaluronidase (HD) have been created with the help of ionization radiation. The drugs' effect on the function of progenitor cells of different classes and regenerative activity of these substances have been described. Hepatoprotective, cerebroprotective and hemostimulating effects of imG-CSF and hep Read More