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image of Fabrication and Efficacy Assessment of a Combination of Polyherbal Facewash Gels for the Treatment of Propionibacterium acnes

Abstract

Introduction

is also referred to as margosa or neem. It is found throughout the Indian subcontinent. L. (family: ), sometimes referred to as Bael in Hindi, is a crucial food plant in India. The fruit has traditionally been used for the treatment of inflammation, diabetes, respiratory disorders, diarrhea, and dysentery. fruits are abundant in coumarins, carotenoids, terpenoids, and flavonoids. The plant referred to as or tea, is part of the family and is often grown in tropical and subtropical regions.

Objective

Acne is a prolonged inflammatory condition of the skin that has a significant negative influence on patients' quality of life all over the world. Although it is most commonly seen in young people, it may impact people of any age. Herbal anti-acne facewash gels were prepared using Carbopol 934 and extracts from , L., and .

Materials and Methods

The anti-acne facewash gel formulations were prepared in five different concentrations of 1%, 0.90%, 0.80%, 0.60%, and 0.50%, labeled as F1, F2, F3, F4, and F5, respectively.

Results

The anti-acne properties of the formulations were evaluated. The outcomes demonstrated gels to have an excellent spreading coefficient, a great physical appearance, and be non-irritating. Standard commercial formulations were used to investigate the effectiveness.

Conclusion

Unlike marketed formulations, the developed formulation 3 (F3) demonstrated an excellent spreading coefficient and good % extrudability. It has been shown to be a more potent and effective polyherbal anti-acne facewash gel for treating acne. In recent years, there has been a rise in the patenting of herbal formulations, and several and studies have produced scientific proof of their medicinal efficacy. This work discusses many patented herbal compositions and how they might be used therapeutically to treat different diseases.

© 2025 Bentham Science Publishers
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2025-03-03
2025-05-23

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/content/journals/raddf/10.2174/0126673878340038250224063731
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Fabrication and Efficacy Assessment of a Combination of Polyherbal Facewash Gels for the Treatment of Propionibacterium acnes
Bentham Science Publishers ; https://doi.org/10.2174/0126673878340038250224063731
/content/journals/raddf/10.2174/0126673878340038250224063731
/content/journals/raddf/10.2174/0126673878340038250224063731
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  • Article Type:     Research Article
Keywords: patent ; carbopol ; Azadirachta indica ; Camellia sinensis ; Aegle marmelos L. ; Acne

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