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2000
Volume 16, Issue 11
  • ISSN: 1570-1786
  • E-ISSN: 1875-6255

Abstract

Novel aza-heterocyclic substituted dehydroepiandrosterone derivatives were synthesized through a three-step reaction sequence. Some new O-alkylated 4-hydroxybenzaldehydes were synthesized from the reaction of substituted benzaldehydes with dihalogen compounds which have different chain lengths. 16-Arylidene steroids were synthesized from the base-catalyzed aldol condensation of O-alkylated 4-hydroxybenzaldehydes and dehydroepiandrosterone. New indolyl and benzimidazolyl substituted steroid derivatives as hybrid molecules were obtained from the reaction of 16-arylidene steroids with indole or benzimidazole.

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/content/journals/loc/10.2174/1570178616666190305130217
2019-11-01
2025-07-14
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