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Phosphomolybdic Acid (PMA)-catalyzed One-pot Synthesis of 2,3-Dihydroquinazolines
- Source: Letters in Organic Chemistry, Volume 16, Issue 8, Aug 2019, p. 683 - 687
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- 01 Aug 2019
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Abstract
We have developed a new method for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in good to excellent yields via phosphomolybdic acid (PMA)-catalyzed cyclocondensation of 2- aminobenzamides with aldehydes or ketones in N,N-dimethylformamide (DMF) at room temperature. The present method proves to be efficient in terms of short reaction time, high yield, simple workup and easy purification.
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