Skip to content
2000
Volume 15, Issue 5
  • ISSN: 1570-1786
  • E-ISSN: 1875-6255

Abstract

Direct hydroxymethylation of C=N double bonds including imines, nitrones, oximes, hydrazones and iminium salts is a less explored synthetic approach to 1,2-amino alcohols that provides good alternatives to the classical methods. The review deals with nucleophilic additions of organometallic hydroxymethyl reagents and lithiated alkoxyallenes to C=N double bonds. Reductive cross couplings between C=N double bonds and aldehydes or ketones are also discussed.

Loading

Article metrics loading...

/content/journals/loc/10.2174/1570178614666171121144234
2018-05-01
2025-07-07
Loading full text...

Full text loading...

/content/journals/loc/10.2174/1570178614666171121144234
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test