Green and Highly Efficient One-Pot Synthesis of Some New Bis Thiazolidinones

A high efficient and environmentally friendly procedure for the production of bis thiazolidinones has been developed. This synthetic approach involves the simple condensation of an appropriate dialdehyde and N,N'-diarylthioureas with chloroacetyl chloride in eutectic salts as a promoter and solvent at 80°C. All products were obtained in good to excellent yields. Structures of these compounds were established on the basis of IR, 1H-NMR, 13C-NMR and by elemental analysis.