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- ISSN: 1570-1786
- E-ISSN: 1875-6255
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Regioselective Alkylation of Pyrrole with 2-Benzylidenemalononitriles Catalyzed by Cu(OTf)2
- Source: Letters in Organic Chemistry, Volume 5, Issue 3, Apr 2008, p. 165 - 168
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- 01 Apr 2008
Abstract
Copper triflate was used as catalyst for the addition of pyrrole to 2-benzylidenemalononitrile and its substituted derivatives. 2-Alkylated pyrrole derivatives were regioselectively obtained in mild reaction conditions. The addition reactions were found to be highly dependent on the substituents of the phenyl group.
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