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Regioselective Synthesis of Biologically Important Scaffold Spiro [Indole- Perimidines]: An Antitumor Agents
- Source: Letters in Organic Chemistry, Volume 4, Issue 5, Jul 2007, p. 378 - 383
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- 01 Jul 2007
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Abstract
Regioselective synthesis of spiro [indole -3(3H), 2' (3H)perimidine]2'(1H)one (4a-e) for potential application in cancer treatment \ under conventionally and microwave irradiation using different solvents/solid support has been studied. A judicious choice of the reaction conditions allowed the titled product 4a-e to be generated in excellent yields.
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