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Microwave Accelerated Multicomponent Synthesis for a Novel Scaffold of Monastrol Analogues
- Source: Letters in Organic Chemistry, Volume 4, Issue 5, Jul 2007, p. 357 - 361
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- 01 Jul 2007
Abstract
A highly efficient and environmentally benign reaction of dimedone with various aldehydes and Narylthioureas to afford monastrol analogues is revealed. The reaction is found to be sensitive towards the steric and electronic effects of the substituents in variable components. A quantitative optimization of catalytic support is also presented.
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